Cyanide Detoxifying Enzyme: Rhodanese

Chaudhary, Mayank; Gupta, Reena

doi:10.2174/2211550111201040327

Cited by 12 publications

(9 citation statements)

References 49 publications

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“…Thus, one can regard SCN as a pseudohalogen. It is known that thiocyanate, SCN – , is much less toxic and can be used as an antidote of CN – . It has been shown experimentally that SCN – can be effectively removed from aqueous solutions by using low-cost natural waste biomass .…”

Section: Results and Discussionmentioning

confidence: 99%

“…It is known that thiocyanate, SCN − , is much less toxic and can be used as an antidote of CN − . 13 It has been shown experimentally that SCN − can be effectively removed from aqueous solutions by using low-cost natural waste biomass. 28 Interestingly, SCN − has recently been used to replace iodine in the organic− inorganic hybrid perovskites to produce CH 3 NH 3 PbI(SCN) 2 , 14 making a leap forward in solving the long-standing problem of degradation of the perovskite solar-cell materials exposed to moisture.…”

Section: Resultsmentioning

confidence: 99%

“…However, the cyanide ion CN − is highly toxic which will make it difficult to synthesize B 12 (CN) 12 2− in experiment. In this paper, by making use of the accumulated knowledge in biological detoxification of CN − and materials design of perovskite solar cells, 13,14 we report a new set of nontoxic ultrastable (di)anions with improved properties compared to B 12 (CN) 12 2− and CB 11 (CN) 12 2− . We note that the giant stability of B 12 (CN) 12 2− is achieved by satisfying two electron counting rules, simultaneously.…”

Section: Introductionmentioning

confidence: 99%

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B₁₂(SCN)₁₂^–: An Ultrastable Weakly Coordinating Dianion

Fang

Jena

2017

J. Phys. Chem. C

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Stable dianions that are weakly coordinating with metal ions are not common. In this work, we show that the thiocyanate SCN − anion, known for its detoxification property of cyanide CN − and antidegradation property of perovskite solarcell materials, can also be used to produce a new set of weakly coordinating B 12 (SCN) 12 − dianion complexes which are potential candidates for the anionic part inside the electrolytes of metal-ion, especially the magnesium-ion-based, batteries.

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Section: Results and Discussionmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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B₁₂(SCN)₁₂^–: An Ultrastable Weakly Coordinating Dianion

Fang

Jena

2017

J. Phys. Chem. C

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“…Representative genes involved in antioxidation and detoxification were also found to be positively selected in S. crosnieri between HV and CS. Enzymes encoded by these genes include Trxs which act as antioxidants by catalyzing the reduction of other proteins by cysteine thiol-disulfide exchange [49], rhodanese that functions to detoxify cyanide into relatively nontoxic thiocyanate [50], and GSTs involved in the cellular detoxification of various endogenous and exogenous electrophilic compounds [51]. As in GST, four putative GST classes (mu, sigma, theta, and kappa) were identified in S. crosnieri transcriptomes based on phylogenetic analysis of GSTs among different arthropod species (Fig.…”

Section: Discussionmentioning

confidence: 99%

Transcriptomic analysis reveals insights into deep-sea adaptations of the dominant species, Shinkaia crosnieri (Crustacea: Decapoda: Anomura), inhabiting both hydrothermal vents and cold seeps

2019

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Background Hydrothermal vents and cold seeps are typical deep-sea chemosynthetically-driven ecosystems that allow high abundance of specialized macro-benthos. To gather knowledge about the genetic basis of adaptation to these extreme environments, species shared between different habitats, especially for the dominant species, are of particular interest. The galatheid squat lobster, Shinkaia crosnieri Baba and Williams, 1998, is one of the few dominant species inhabiting both deep-sea hydrothermal vents and cold seeps. In this study, we performed transcriptome analyses of S. crosnieri collected from the Iheya North hydrothermal vent (HV) and a cold seep in the South China Sea (CS) to provide insights into how this species has evolved to thrive in different deep-sea chemosynthetic ecosystems. Results We analyzed 5347 orthologs between HV and CS to identify genes under positive selection through the maximum likelihood approach. A total of 82 genes were identified to be positively selected and covered diverse functional categories, potentially indicating their importance for S. crosnieri to cope with environmental heterogeneity between deep-sea vents and seeps. Among 39,806 annotated unigenes, a large number of differentially expressed genes (DEGs) were identified between HV and CS, including 339 and 206 genes significantly up-regulated in HV and CS, respectively. Most of the DEGs associated with stress response and immunity were up-regulated in HV, possibly allowing S. crosnieri to increase its capability to manage more environmental stresses in the hydrothermal vents. Conclusions We provide the first comprehensive transcriptomic resource for the deep-sea squat lobster, S. crosnieri , inhabiting both hydrothermal vents and cold seeps. A number of stress response and immune-related genes were positively selected and/or differentially expressed, potentially indicating their important roles for S. crosnieri to thrive in both deep-sea vents and cold seeps. Our results indicated that genetic adaptation of S. crosnieri to different deep-sea chemosynthetic environments might be mediated by adaptive evolution of functional genes related to stress response and immunity, and alterations in their gene expression that lead to different stress resistance. However, further work is required to test these proposed hypotheses. All results can constitute important baseline data for further studies towards elucidating the adaptive mechanisms in deep-sea crustaceans. Electronic supplementary material The online version of this article (10.1186/s12864-019-5753-7) contains supplementary material, which is available to authorized users.

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“…Table 5). They further harbor genes for detoxification, like those coding for cyanide hydratases/nitrilases (Howden and Preston 2009) and rhodanese (Chaudhary and Gupta 2012).…”

Section: Genes and Proteins Related To Stress Tolerancementioning

confidence: 99%

Interaction between endophytic Proteobacteria strains and Serendipita indica enhances biocontrol activity against fungal pathogens

et al. 2020

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Aims Plants host communities of fungal and bacterial endophytes, establishing a complex network of multipartite interactions, but the mechanisms whereby they interact are poorly understood. Some fungi, such as the beneficial mycorrhiza-like fungus Serendipita (=Piriformospora) indica, can be helped by bacteria for establishment, survival and colonization. Although this fungus harbors a Rhizobium as an endofungal bacterium, we hypothesized that other bacteria might also establish associations with the fungus and combining S. indica with bacteria might enhance plant growth and health. Methods The interactions among S. indica and four e n d o p h y t i c P r o t e o b a c t e r i a b e l o n g i n g t o Methylobacterium, Tardiphaga, Rhodanobacter and Trinickia spp. were characterized in vitro and for their effect on tomato growth and biocontrol of Fusarium oxysporum and Rhizoctonia solani. Possible mechanisms behind these interactions were described based on genome and microscopic analyses, using fungal and bacterial strains tagged with fluorescent markers. Results All bacteria stimulated S. indica growth in vitro. Moreover, several of the bacteria stimulated growth of tomato plants, but co-inoculations with S. indica and bacteria did not perform better than single inoculations. Contrarily, combinations of S. indica and bacteria significantly reduced disease progression of fungal pathogens. These microbes seem to cooperate in the process of root colonization for instance by increasing fungal sporulation and hyphae expansion, showing multipartite interaction between microbes and plants. Interestingly, the strain of Trinickia internally colonizes spores of S. indica as an endofungal bacterium during in vitro-co-culturing, suggesting further that the fungus might acquire formerly unrecognized genera of bacteria and genome analysis of the bacteria revealed many genes potentially involved in fungal and plant growth stimulation, biocontrol and root colonization, highlighting putative mechanisms of plantfungal-bacterial interaction. Conclusions Our study represents an important step towards unraveling the complex interactions among plants, S. indica, endophytic bacteria and fungal pathogens, and indicates that adding bacteria to fungal inoculum could have a remarkable impact on the plantS. indica symbiosis.

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Cyanide Detoxifying Enzyme: Rhodanese

Cited by 12 publications

References 49 publications

B₁₂(SCN)₁₂^–: An Ultrastable Weakly Coordinating Dianion

B₁₂(SCN)₁₂^–: An Ultrastable Weakly Coordinating Dianion

Transcriptomic analysis reveals insights into deep-sea adaptations of the dominant species, Shinkaia crosnieri (Crustacea: Decapoda: Anomura), inhabiting both hydrothermal vents and cold seeps

Interaction between endophytic Proteobacteria strains and Serendipita indica enhances biocontrol activity against fungal pathogens

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Cyanide Detoxifying Enzyme: Rhodanese

Cited by 12 publications

References 49 publications

B12(SCN)12–: An Ultrastable Weakly Coordinating Dianion

B12(SCN)12–: An Ultrastable Weakly Coordinating Dianion

Transcriptomic analysis reveals insights into deep-sea adaptations of the dominant species, Shinkaia crosnieri (Crustacea: Decapoda: Anomura), inhabiting both hydrothermal vents and cold seeps

Interaction between endophytic Proteobacteria strains and Serendipita indica enhances biocontrol activity against fungal pathogens

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B₁₂(SCN)₁₂^–: An Ultrastable Weakly Coordinating Dianion

B₁₂(SCN)₁₂^–: An Ultrastable Weakly Coordinating Dianion