Cuticular changes in dermatomyositis. A clinical sign

Samitz, M. H.

doi:10.1001/archderm.110.6.866

Cited by 9 publications

(1 citation statement)

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“…Resolution of NFC changes in DM patients with treatment and its reappearance could be a sign of the disease progression which signifies the severity of the disease. In DM, patient's cuticle is first to be healed following treatments, so its reappearance during follow‐up is considered an indicator of relapse 20,21 . It is suggested that 74% of DM patients exhibit an SD pattern of nail fold capillary 4 .…”

Section: Discussionmentioning

confidence: 99%

Assessment of nail fold capillary changes by hand‐held dermoscopy in adult dermatomyositis: A single‐centre prospective study

Paudyal,

Yang,

Zheng

et al. 2023

Aust J Dermatology

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BackgroundHand‐held dermoscopy is a valuable tool for dermatologists, but it has been rarely used to assess the nail fold capillary (NFC) in patients with dermatomyositis (DM).MethodsPatients were collected from the Department of Dermatology and Venereology from July 2020 to July 2021, and the follow‐up was conducted until January 2022. Demographic features, disease activity and NFC changes were analysed using a hand‐held dermoscopy.ResultsThe most common NFC finding in our study was bushy capillary (87.0%). There was no significant improvement in scleroderma–dermatomyositis (SD)‐like nail fold changes or enlarged capillaries from baseline to 12 weeks of treatment (p > 0.05) or from 12 weeks to 24 weeks of treatment (p > 0.05), but there was a significant improvement from baseline to 24 weeks of treatment (p < 0.05). The avascular area did not improve from baseline to 12 weeks of follow‐up, but the changes were significant from 12 weeks to 24 weeks of treatment (p < 0.05) and baseline to 24 weeks of treatment (p < 0.05). Periungual erythema improved significantly from baseline to 12 weeks of treatment (p < 0.05) and baseline to 24 weeks of treatment (p < 0.05), but it did not improve significantly from 12 weeks to 24 weeks of treatment (p > 0.05). There was no significant difference in disease activity between patients with or without specific NFC changes. However, some NFC features improved as disease activity decreased.ConclusionDermoscopy of NFC is a cost‐effective option for the preliminary diagnosis of DM. Further, long‐term follow‐up is necessary to study the relationship between disease activity and NFC changes.

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Section: Discussionmentioning

confidence: 99%