1990
DOI: 10.1001/archderm.126.11.1449
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Cutaneous T-cell lymphoma (parapsoriasis en plaque). An association with pityriasis lichenoides et varioliformis acuta in young children

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Cited by 48 publications
(49 citation statements)
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“…This hypothesis is supported by the rare development of malignant lymphomas in patients with PLEVA. [12][13][14][15] Another possibility is that PLEVA is closely related to LyP, which clearly has a malignant potential and was a clonal T-cell disorder in most cases. 21 This hypothesis is supported by the similar clinical presentations and the possible occurrence of both PLEVA and LyP in the same patient.…”
Section: Commentmentioning
confidence: 99%
See 1 more Smart Citation
“…This hypothesis is supported by the rare development of malignant lymphomas in patients with PLEVA. [12][13][14][15] Another possibility is that PLEVA is closely related to LyP, which clearly has a malignant potential and was a clonal T-cell disorder in most cases. 21 This hypothesis is supported by the similar clinical presentations and the possible occurrence of both PLEVA and LyP in the same patient.…”
Section: Commentmentioning
confidence: 99%
“…6,10,11 In this latter case, a vigorous host immune reaction might prevent PLEVA from evolving into a true cutaneous lymphoma, 6 although such an outcome has sometimes occurred in acute [12][13][14] and chronic forms of pityriasis lichenoides. 15,16 The host immune response could be represented by the usual predominance of CD8 + lymphocytes in the dermal infiltrate.…”
mentioning
confidence: 99%
“…Despite its lymphoproliferative nature, PLEVA is a clinically benign entity with no significantly documented association with malignant lymphoma, 9 except for a few, poorly documented case reports. 14 Another recent study evaluated clonality in cases of PLC 15 : 6 cases of PLC were analyzed using a frozen section-immunoperoxidase technique and PCR/ denaturing gradient gel electrophoresis (PCR/DGGE). Of these, 3 demonstrated a monoclonal gene rearrangement.…”
mentioning
confidence: 99%
“…43 Tumor cells contain TIA-1, granzyme B, and/or perforin. 64,65 Clusterin is a marker of ALCL 66 and has been found in primary c-ALCL but not in Hodgkin's lymphoma. Most systemic ALCL cases are positive for ALK nuclear and cytoplasmic staining, but there are variants with only cytoplasmic staining.…”
Section: Distinction Between Cutaneous and Systemic Alclmentioning
confidence: 99%