Cutaneous metastatic adenocarcinoma of gallbladder origin

Abstract

Cutaneous metastases developed in a 74-year-old woman from an adenocarcinoma of the gallbladder. A biopsy specimen of a cutaneous nodule showed the presence of systemic cancer. Results of a histopathologic examination, along with the autopsy findings, established that the cutaneous metastasis was of gallbladder origin. This article reports the extreme rarity of metastases from a cancer of the gallbladder to the skin.

Cerebriform nodular amelanotic metastases of malignant melanoma: a challenge in differential diagnosis of a rare variant

“… 2 Rarely, inflammatory and sclerodermoid lesions have also been also reported, 3 predominantly originating from adenocarcinomas of the pulmonary, gastrointestinal, genitourinary and oropharyngeal system, the thyroid and the prostate gland. 4–13 In men, cutaneous metastases mainly derive from carcinoma of the lung, the gastrointestinal system and the oropharynx, whereas skin metastases in women originate predominantly from carcinomas of the breast, the colon, the lung or the ovary 14–16 ( Table 1).…”

Cutaneous Metastasis of Gallbladder Adenocarcinoma in a Patient with Chronic Lymphocytic Leukemia: A Case Report and Review of the Literature

“…Typically, the metastatic lesions are non-tender, erythematous, nodular, and either cutaneous or subcutaneous. Padilla et al7 reported on one patient that had ulcerated epidermal invasion. In various case reports, Padilla et al7 reported that the lesions were inflammatory skin lesions resembling cellulitis or erythema annulare, condyloma, herpes zoster, epidermal inclusion cysts, and ulcerative lesions other than this typical appearance.…”

“…Padilla et al7 reported on one patient that had ulcerated epidermal invasion. In various case reports, Padilla et al7 reported that the lesions were inflammatory skin lesions resembling cellulitis or erythema annulare, condyloma, herpes zoster, epidermal inclusion cysts, and ulcerative lesions other than this typical appearance. In the presented case 0.5~2 cm erythematous mass cutaneous lesions that projected from the skin with a thin peduncle were present and their localization did correspond with data in the literature.…”

Cutaneous metastasis from visceral malignancy: A rare presentation

“…[ 9 ] The incidence of metastasis of adenocarcinoma of gall bladder to the skin is even rarer, with only a few cases reported. [ 2 – 6 ]…”

“…[ 1 ] The incidence of metastasis of adenocarcinoma of gall bladder to the skin is rare, with only a few reported cases. [ 2 – 6 ] The skin lesions are easily accessible to fine needle aspiration cytology (FNAC) and may help in the diagnosis of the primary. We report two cases where FNAC of the cutaneous deposits helped in diagnosing the primaries in the gall bladder.…”