"Cutaneous manifestations of internal malignant tumors" by Becker, Kahn and Rothman, June 1942. Commentary: Migratory necrolytic erythema

Im, Braverman

doi:10.1001/archderm.118.10.784

Cited by 13 publications

(13 citation statements)

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“…Glucagonoma syndrome is elicited by a glucagon‐secreting tumor, and may be clinically associated with hyperglucagonemia, necrolytic migratory erythema (NME), recent onset of diabetes mellitus, anemia, weight loss, and diarrhea. The NME is widespread, with predilection for the perineum, abdomen, groin, buttocks, and lower extremities (10–18). Frequently, these areas may be dry or fissured as a result (10–18).…”

Section: Glucagonoma Syndromementioning

confidence: 99%

“…The NME is widespread, with predilection for the perineum, abdomen, groin, buttocks, and lower extremities (10–18). Frequently, these areas may be dry or fissured as a result (10–18). The eruption begins with uneven patches of intense erythema, superficial flaccid vesicles, and bullae that later rupture and create extensive erosions or exudative, crusted plaques.…”

Section: Glucagonoma Syndromementioning

confidence: 99%

“…The eruption begins with uneven patches of intense erythema, superficial flaccid vesicles, and bullae that later rupture and create extensive erosions or exudative, crusted plaques. Other mucocutaneous findings are cheilosis, atrophic glossitis, oral mucosal inflammation, and alopecia (10–18). All stages of lesion development may be observed simultaneously.…”

Section: Glucagonoma Syndromementioning

confidence: 99%

“…Almost all patients with NME have a pancreatic alpha cell tumor, and elevated glucagon levels. In approximately one‐half of patients, there are alpha cell tumor liver metastases at the time of diagnosis (10–18). The histopathologic features of NME are nonspecific and include: epidermal necrosis, subcorneal pustules, confluent parakeratosis, epidermal hyperplasia, marked papillary dermal hyperplasia in a psoriasiform pattern, angioplasia of the papillary dermis, and suppurative folliculitis.…”

Section: Glucagonoma Syndromementioning

confidence: 99%

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Diagnosis and treatment of cutaneous paraneoplastic disorders

Velez

Howard

2010

Dermatologic Therapy

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The skin plays a critical role in the detection of internal malignances. Cutaneous signs of these disorders afford clinicians opportunities for early diagnosis and treatment. We aim to succinctly review the recognition, diagnosis, and treatment of selected cutaneous paraneoplastic diseases. Skin disorders that may be associated with paraneoplastic syndromes include: cutaneous metastases, tripe palms, Sweet's syndrome, glucagonoma, Paget's disease and extramammary Paget's disease, acanthosis nigricans, Birt-Hogg-Dube syndrome, basal cell nevus syndrome, Bazex syndrome (acrokeratosis paraneoplastica), carcinoid syndrome, Cowden's disease(multiple hamartoma syndrome), dermatomyositis, erythema gyratum repens, ichthyosis aquisita, von Recklinghausen's disease, pityriasis rotunda, pyoderma gangrenosum, Quincke's edema (angioedema and paraneoplastic uricaria), paraneoplastic pemphigus, Degos' disease, superior vena cava syndrome, Werner's syndrome, diffuse normolipemic plane xanthomas, and yellow nail syndrome. Treatment for these disorders depends on the nature and anatomic distribution of the primary neoplastic process.

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Section: Glucagonoma Syndromementioning

confidence: 99%

Section: Glucagonoma Syndromementioning

confidence: 99%

Section: Glucagonoma Syndromementioning

confidence: 99%

Section: Glucagonoma Syndromementioning

confidence: 99%

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Diagnosis and treatment of cutaneous paraneoplastic disorders

Velez

Howard

2010

Dermatologic Therapy

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“…Since its first description by Becker in 1942 [ 1 ], around 300 cases of glucagonoma and glucagonoma syndrome have been described. Consequently, only few surgeons and physicians will be faced with this peculiar diagnosis.…”

Section: Introductionmentioning

confidence: 99%

Glucagonoma and Glucagonoma Syndrome: A Case Report with Review of Recent Advances in Management

Al-Faouri

Ajarma

Alghazawi

et al. 2016

Case Reports in Surgery

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The rarity of glucagonoma imposes a challenge with most patients being diagnosed after a long period of treatment for their skin rash (months-years). Awareness of physicians and dermatologists of the characteristic necrolytic migratory erythema often leads to early diagnosis. Early diagnosis of glucagonoma even in the presence of resectable liver metastases may allow curative resection. Herein, we present a typical case of glucagonoma treated at our center and review the literature pertinent to its management.

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Pseudoglucagonoma Syndrome in a Patient With Malnutrition

Bak¹,

Ahn²

2005

Arch Dermatol

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"Cutaneous manifestations of internal malignant tumors" by Becker, Kahn and Rothman, June 1942. Commentary: Migratory necrolytic erythema

Cited by 13 publications

References 0 publications

Diagnosis and treatment of cutaneous paraneoplastic disorders

Diagnosis and treatment of cutaneous paraneoplastic disorders

Glucagonoma and Glucagonoma Syndrome: A Case Report with Review of Recent Advances in Management

Pseudoglucagonoma Syndrome in a Patient With Malnutrition

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