Cutaneous manifestations of chikungunya during a recent epidemic in Calicut, north Kerala, south India

Riyaz, Najeeba; Riyaz, A; Rahima,; Latheef, Ettappurath N Abdul; Anitha, P.; Aravindan, K P; Nair, Arun; Shameera, P

doi:10.4103/0378-6323.72466

Cited by 77 publications

(85 citation statements)

References 11 publications

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“…Chikungunya fever may be seen in all age groups and both sexes. In current study, males outnumbered females similar to other studies [5,8] while both sexes were equally affected in another study [9]. Generalized dark colored pigmentation was the most common finding after the fever subsided.…”

Section: Resultssupporting

confidence: 86%

“…Different types of pigmentation have been reported in chikungunya. It was most common presentation reported in study by Inamdar et al [8] and second most common presentation in study by Riaz et al [5]. Similarly in present study chief complaint of adult was pigmentation over nose, face, centre of upper lip, centrofacial, over palm, sole, eyelid and dorsum of finger.…”

Section: Post-chikungunya Pigmentation In Adultssupporting

confidence: 71%

“…Knowledge of this pigmentary change is essential, both amongst the physicians and dermatologists, since it can act as an indicator for an undetected outbreak of chikungunya fever; especially in a health set up where it is not possible to screen every case of viral fever for chikungunya fever. Hyperpigmentation associated with chikungunya fever is macular and most commonly affects nose and cheeks [5,6]. It may develop soon after the rash has resolved, and has an acute onset [6].…”

Section: Introductionmentioning

confidence: 99%

“…PCP may occur in the form of discrete macules, freckle-like, diffuse, flagellate, Addisonian type of palmar pigmentation, periorbital melanosis and pigmentation of pre-existing acne lesions [5,6]. Involvement of centrofacial face (nose and cheeks) mimics melasma and in a busy outpatient department (OPD), is likely to be missed especially if proper history is not taken [5]. Patients with PCP give a history of high grade fever 2-4 weeks before onset, acute onset of hypermelanosis and many times, persistent asthenia and joint pain even after defervescence of fever.…”

Section: Introductionmentioning

confidence: 99%

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Study of cutaneous manifestation of chikungunya and its serological correlation

Shinde¹,

Popere

2018

Int Jour of Biomed Res

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Aim: To assess the hyperpigmentation after fever and joint pain as a cutaneous marker of chikungunya fever and to assess with serological correlation. Methods: A total of 15 patients comprised of 9 males, 6 females and neonate have aged between 14 days to 60 years presented with the pigmentation after the fever subsided were enrolled in the study. The diagnosis of chikungunya was made by detecting virus specific IgM ELISA in the serum. Results: Serological immunoglobulin M enzyme -linked immunosorbent assay (IgM ELISA) test or chikungunya virus was positive in all the patients. Generalized dark coloured pigmentation was the most common finding after the fever subsided. On examination, out of 15 cases, in most of the cases, hyperpigmentation was observed all over the body with the facial involvement. Few cases showed pigmentation over nose, centre of upper lip, on palm, sole, eyelid, dorsum, centrofacial, reticulate pattern on the face and blotchy pigmentation. Conclusion:The presence of pigmentation after fever and joint pain helps to make a retrospective diagnosis of chikungunya fever and this may be considered as a cutaneous marker of chikungunya fever in recent past.

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Section: Resultssupporting

confidence: 86%

Section: Post-chikungunya Pigmentation In Adultssupporting

confidence: 71%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Study of cutaneous manifestation of chikungunya and its serological correlation

Shinde¹,

Popere

2018

Int Jour of Biomed Res

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“…Pigmentary changes have been one of the common presenta ons in viral illness 1,2,3,4,5 .Mechanism of pigmenta on can be post infl ammatory 5 . An increase in intraepidermal melanin dispersion/reten on triggered by the virus has also been suggested 6 .…”

mentioning

confidence: 99%

Acute Centro-facial Pigmentation – A sign of Viral Exanthem ?: Case Reports

Shilpakar¹,

Velugotla²,

Sachdev³

2017

Nepal J Dermatol Venereol & Leprol

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We report two cases of abrupt onset centro-facial pigmentation associated with acute viral fever and arthralgia. Review of literature yielded reports of similar pigmentation along with other dermatological manifestations like maculopapular rash, vesiculobullous lesions etc. In our cases centrofacial pigmentation confined to nose was the only presenting symptom and required treatment from patient's perspective.Centro-facial melanosis may be considered as a sign of acute viral fever which could require specific treatment.The aim of our report is to widen the vision of clinicians in considering abrupt onset of centro-facial melanosis as a presenting symptom in an acute sero-negative viral fever with arthralgia.

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