Cutaneous manifestations in the current pandemic of coronavirus infection disease (COVID 2019)

Morey-Olivé, Miriam; Espiau, María; Mercadal-Hally, María; Lera-Carballo, Esther; García-Patos, Vicenç

doi:10.1016/j.anpede.2020.04.002

Cited by 73 publications

(97 citation statements)

References 4 publications

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“…Previous studies report cutaneous involvement in a range from 0.2% 4 to 20% 5 . Based on the growing reports in the literature, we can argue that cutaneous symptoms of the new coronavirus are similar to those of other common viral infections 3 . Two different mechanisms are primarily suggested to explain cutaneous lesions.…”

Section: Figurementioning

confidence: 88%

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A unilateral purpuric rash in a patient with COVID ‐19 infection

Karaca

Yaylı

Çalışkan

2020

Dermatologic Therapy

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Dear Editor, Coronavirus disease (COVID-19) of 2019 caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was declared as a pandemic by the World Health Organization on March 11, 2020. Currently, it continues to exist as a global problem. 1 While screening the people contacted with a patient diagnosed as COVID-19 infection, we identified a 58-year-old male with a positive polymerase chain reaction (PCR) for SARS-CoV-2. At the time of diagnosis, the patient did not have any infection-related complaints. However, the computed tomography scan of the chest was typical of COVID-19. Ground glass opacities were observed in both lung parenchyma. On

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Section: Figurementioning

confidence: 88%

“…However, the cutaneous effects of the infection have not been clarified yet. Furthermore, no evidence exists that the degree of cutaneous involvement is related to the severity of the disease 3 . Previous studies report cutaneous involvement in a range from 0.2% 4 to 20% 5 .…”

Section: Figurementioning

confidence: 99%

A unilateral purpuric rash in a patient with COVID ‐19 infection

Karaca

Yaylı

Çalışkan

2020

Dermatologic Therapy

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“…In addition, there are reports of the erythema multiforme type 7 . A search of the PubMed database retrieved only seven case reports describing COVID‐19 patients with an erythema that included basic patient information such as sex, age and time course of rash; 8–14 these reports are summarized in Table 1. The mean patient age was 47.1 years, with a range of 6–67 years.…”

Section: Discussionmentioning

confidence: 99%

Three cases of COVID‐19 patients presenting with erythema

Tamai¹,

Maekawa²,

Goto³

et al. 2020

The Journal of Dermatology

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Individuals infected with the novel coronavirus (Severe Acute Respiratory Syndrome Coronavirus 2 [SARS-CoV-2]) who develop coronavirus disease 2019 (COVID-19) experience many symptoms; however, cutaneous manifestations are relatively rare. The authors encountered three patients with COVID-19 who presented with erythema and suspected viral rash. In all cases, erythema appeared after the onset of the initial symptoms of COVID-19. Erythema was considered to be caused by COVID-19 and not a drug-induced eruption because, in all cases, erythema was relieved merely by external medicine and oral antihistamines, without discontinuing the original medication. The authors' hospital accepted 69 COVID-19 patients between 22 February 2020 and 31 May 2020 and, of these, three (4.3%) exhibited eruptions, and all cases presented erythema. Except for seven patients who exhibited positive nasopharyngeal swab tests for SARS-CoV-2 RNA but no symptoms, three (4.8%) of the remaining 62 patients exhibited erythema. Although various types of eruptions have been reported in patients with COVID-19, erythema was the only type in our patients. Erythema in the three patients exhibited many similarities to that previously reported in COVID-19 patients, particularly in the manner it appeared and disappeared. For these reasons, these three cases were considered typical examples of erythema in patients with COVID-19. Considering previous studies and the three cases reported here, there is a high probability that SARS-CoV-2 can cause erythema.

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“…There is a case report of an acute urticarial rash in a 2‐month‐old girl from Spain that began on the face and spread all over the body except mucosa and palmoplantar skin. It disappeared after 9 days 33 …”

Section: Chickenpox‐like Rashmentioning

confidence: 97%

Cutaneous signs in COVID ‐19 patients: A review

Wollina

Karadağ

Rowland‐Payne

et al. 2020

Dermatologic Therapy

259

286

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Coronavirus disease pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) primarily affects the epithelium of the airways.With the increasing involvement of dermatologist in management of this crisis, cutaneous symptoms gained more and more attention. In this review, we will describe cutaneous symptoms of patients of all ages in association with COVID-19.We will focus on such disorders that are caused by direct action of SARS-CoV-2 on tissues, complement, and coagulation system and on nonspecific eruption of the systemic viral infection. Drug-induced reactions are only mentioned in the differential diagnoses. Although more systematic investigations are warranted, it becomes clear that some symptoms are clinical signs of a milder COVID-19 course, while others are a red flag for a more severe course. Knowledge of the cutaneous manifestations of COVID-19 may help in early diagnosis, triage of patients, and risk stratification.

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Cutaneous manifestations in the current pandemic of coronavirus infection disease (COVID 2019)

Cited by 73 publications

References 4 publications

A unilateral purpuric rash in a patient with COVID ‐19 infection

A unilateral purpuric rash in a patient with COVID ‐19 infection

Three cases of COVID‐19 patients presenting with erythema

Cutaneous signs in COVID ‐19 patients: A review

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