1981
DOI: 10.1001/archderm.117.11.719
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Cutaneous malignant mixed tumor

Abstract: Two cases of cutaneous malignant mixed tumor occurred in a 70-year-old man and a 69-year-old man. Nine previously described patients with cutaneous malignant mixed tumor resembled the two patients in this report, both clinically and histologically. All cases with adequate long-term follow-up evaluations were characterized by recurrence or metastasis. In contrast to benign mixed tumors, these tumors tend to occur on the extremities, are of larger size, and may exhibit rapid growth. Histologically, cellular atyp… Show more

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Cited by 24 publications
(9 citation statements)
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“…The majority of cases recorded in the English medical literature have been in the form of single case reports [4, 7, 10, 11, 12, 13, 14]. Synonymous terms include malignant mixed tumour of skin [14], cutaneous malignant mixed tumour [15], metastasising chondroid syringoma [16] and aggressive chondroid syringoma [17]. Cases of “atypical mixed tumour of skin” may perhaps represent additional examples of MCS [16].…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…The majority of cases recorded in the English medical literature have been in the form of single case reports [4, 7, 10, 11, 12, 13, 14]. Synonymous terms include malignant mixed tumour of skin [14], cutaneous malignant mixed tumour [15], metastasising chondroid syringoma [16] and aggressive chondroid syringoma [17]. Cases of “atypical mixed tumour of skin” may perhaps represent additional examples of MCS [16].…”
Section: Discussionmentioning
confidence: 99%
“…MCS is classically described as a biphasic tumour with a malignant epithelial component admixed with a benign chondroid mesenchymal component [2]. The malignant epithelial component is characterised by increased cellularity, lack of cellular cohesion, frequent absence of glandular or ductal differentiation, infiltrative growth, necrosis, nuclear pleomorphism and increased mitotic activity [2, 3, 10, 13, 15]. Dermal satellite nodules [6] and osseous metaplasia have also been reported [3].…”
Section: Discussionmentioning
confidence: 99%
“…[56] Although most are benign, malignant forms have been reported. [278] Unlike its benign counterpart, the malignant form occurs predominantly in females, has no age related predilection, and is observed more commonly on the extremities. [279] Only two cases have been reported to occur in the head.…”
Section: Discussionmentioning
confidence: 99%
“…[278] Unlike its benign counterpart, the malignant form occurs predominantly in females, has no age related predilection, and is observed more commonly on the extremities. [279] Only two cases have been reported to occur in the head. [23] Differentiation toward various skin adnexal structures (including hair matrix, hair follicle, apocrine, and sebaceous glands) is rare.…”
Section: Discussionmentioning
confidence: 99%
“…While many tumors have been described in the foot and ankle, chondroid syringoma of the foot has been reported on less than ten occasions and never in commonly referenced orthopaedic journals. 6,7,14,18 However, it is notable that in a review of malignant chondroid syringomas in 2000, 11 of 29 patients presented with primary lesions below the knee. 2 Originally described in 1859 by Bilmuth, eccrine and apocrine variants of chondroid syringoma have been described.…”
Section: Disussionmentioning
confidence: 99%