Cutaneous malignant melanoma and sun exposure. Recent developments in epidemiology

Katsambas, Andreas

doi:10.1001/archderm.132.4.444

Cited by 39 publications

(29 citation statements)

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“…[1][2][3][4][5][6][7][8][9][10][11] O papel da redução da camada de ozono é menos claro. No entanto, alguns estudos sugerem que uma redução em 1% da camada de ozono leva ao aumento da incidência do melanoma, na ordem dos 0,6%.…”

Section: Variávelunclassified

Melanoma Maligno Cutâneo: Estudo Retrospetivo de Sete Anos (2006-2012)

Moreira

Azevedo

et al. 2014

Acta Med Port

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Acta Med Port 2014 Jul-Aug;27(4):480-488 RESUMOIntrodução: O melanoma maligno é a neoplasia cutânea mais agressiva, e a sua incidência tem vindo a aumentar nas últimas déca-das. A possibilidade de cura depende de um diagnóstico atempado, sendo fundamental o conhecimento da sua epidemiologia para a implementação de programas de prevenção primária e deteção precoce do melanoma. ABSTRACTIntroduction: Malignant melanoma is the most aggressive skin cancer and its incidence has been increasing in recent decades. The cure depends on early diagnosis and understanding melanoma epidemiology is of great importance for the implementation of programs of primary prevention and early detection. Material and Methods:We reviewed the clinical cases of primary cutaneous malignant melanoma diagnosed between January 2006 and December 2012 at Centro Hospitalar de São João, in Porto.Results: An overall of 148 cases of melanoma were analyzed and a female predominance was observed (ratio F:M -1.6:1). The average age at diagnosis was 61 years. The locations most frequently affected were the lower limbs and trunk. In males the back was the most frequently involved, while in females the lesions occurred preferentially in the legs. Superficial spreading melanoma prevailed in almost all age groups. There was a predominance of thin melanomas and the mitotic index was intermediate (1-6 mitoses/ mm 2 ) in most patients. The ulceration was present in 22.3% of cases and prevailed in thick melanomas as well in nodular subtype. Most patients present at stage IA. There was progression to metastatic disease in 20 patients. Discussion: The profile of patients with cutaneous melanoma in Centro Hospitalar de São João has characteristics relatively similar to those described in the literature. Conclusion: The prevalence of thin melanomas, generally with a better outcome, is probably the result of an earlier detection.

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Section: Variávelunclassified

Melanoma Maligno Cutâneo: Estudo Retrospetivo de Sete Anos (2006-2012)

Moreira

Azevedo

et al. 2014

Acta Med Port

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“…The epidemiology of melanoma is paradoxical. It has long been suspected that malignant melanoma is associated with exposure to sunlight, and that ultraviolet B (UVB) was the probable causal factor due to its role as the principal factor in reddening and edema of the skin, and its tendency to produce thymidine dinucleotides and other characteristic DNA mutations, (4)(5)(6). Unfortunately, the relationship of sunlight exposure with risk of melanoma may be more complicated than suggested by a simple solar exposure model of aetiology.…”

Section: Introductionmentioning

confidence: 99%

Epidemiologic Evidence for Different Roles of Ultraviolet A and B Radiation in Melanoma Mortality Rates

Garland

Gorham

2003

Annals of Epidemiology

126

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“…2 Because most lifetime sun exposure occurs early in life and childhood sunburns may be an antecedent to melanoma, 3,4 promotion of sun protection among children is particularly important. [5][6][7] Pediatricians working both in their offices and in conjunction with schools and community programs could play an important role promoting sun protection.…”

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confidence: 99%

A Community-based Randomized Trial Encouraging Sun Protection for Children

Dietrich¹,

Olson

Sox³

et al. 1998

Pediatrics

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ABSTRACT. Objective. We evaluated the impact of an intervention promoting sun protection behavior among children 2 to 11 years of age through schools and day care centers, primary care practices, and recreation areas.Methods. Ten towns in New Hampshire were paired, then assigned randomly to intervention or control status. The multicomponent SunSafe intervention was provided to children and caregivers through primary care practices, day care centers, schools, and beach recreation areas. Training support and materials were provided by the SunSafe project, but project staff had no direct contact with children or parents in providing the intervention. All intervention components promoted the same message: avoid the sun between 11 AM and 3 PM, cover up using hats and protective clothing, use sun block with a sun protection factor >15, and encourage sun protection among family and friends. The impact of the intervention was determined by observing children's sun protection behavior at the beach during baseline compared with 1 year later. The primary outcomes of interest were changes in the proportion of children per town using at least some sun protection and changes in the proportion of children fully protected. Children were clustered by town, with the town thus being the unit of analysis.The primary care practice component included one practice meeting for clinicians and staff at which project staff presented background on skin cancer and how to promote its prevention; a sun protection office system manual based on our previous work, which provided specific direction on how to share responsibility among office staff and clinicians in carrying out routines that promote sun protection; and educational posters, pamphlets, and self-adhesive reminder notes designed to enhance sun protection counseling. SunSafe removable tattoos and stickers were offered to children at well-child and illness visits during the summer months.Schools each received three project staff visits: a brief visit with the principal to describe the intervention and to answer questions; an in-service program to educate teachers about skin cancer and to introduce curricular materials; and help with one parent outreach program. Larger day care centers each received one project staff visit. An additional six smaller day care centers received curricular materials through the mail but no visits. Two similar sets of curricular materials were used, one for grade schools and the other for preschools and day care centers. Both emphasized the importance of sun protection rather than the danger of skin cancer. Materials emphasized dynamic activities modeled after the "Slip, Slop, Slap" and "SunSmart" programs and included new material developed to suit regional needs. Both manuals offered structured plans but also provided a variety of activities from which teachers could choose. Teachers agreed to devote a minimum of two class periods to these materials.For recreation areas, lifeguards in each of the intervention communities attended an in-service meeting, dur...

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Cutaneous malignant melanoma and sun exposure. Recent developments in epidemiology

Cited by 39 publications

References 0 publications

Melanoma Maligno Cutâneo: Estudo Retrospetivo de Sete Anos (2006-2012)

Melanoma Maligno Cutâneo: Estudo Retrospetivo de Sete Anos (2006-2012)

Epidemiologic Evidence for Different Roles of Ultraviolet A and B Radiation in Melanoma Mortality Rates

A Community-based Randomized Trial Encouraging Sun Protection for Children

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