Cutaneous Malacoplakia in a Patient With the Acquired Immunodeficiency Syndrome

Wittenberg, Gregory P.

doi:10.1001/archderm.134.2.244

Cited by 10 publications

(3 citation statements)

References 2 publications

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“…Cutaneous involvement is rarely seen, with only 34 cases reported to date, of which two have been in HIV-positive patients. 2,3 Malakoplakia often occurs in the setting of immunosuppressed states such as organ transplantation, malignancies, immunosuppressive drugs and AIDS. In such patients, macrophages fail to phagocytose and digest bacteria adequately.…”

Section: Discussionmentioning

confidence: 99%

“…This may be explained by selective preservation of antimicrobial function of monocytes in HIV. 3,6 In addition, malakoplakia is usually clinically unsuspected and is diagnosed on classical histopathology in most cases. This case underlines the importance of skin biopsy in HIVpositive patients presenting with atypical abscesses, nodules and plaques, especially in the perigenital region without draining lymph node involvement.…”

Section: Discussionmentioning

confidence: 99%

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Cutaneous malakoplakia in an HIV-positive patient

Savant¹,

Amladi²,

Kangle³

et al. 2007

Int J STD AIDS

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Malakoplakia is an uncommon granulomatous infectious disease that is found primarily in the genitourinary tract, but may rarely involve the skin. We report a case of cutaneous malakoplakia in an HIV-positive patient diagnosed on the basis of Michaelis-Gutman bodies. The patient presented with ulcers, draining sinuses and tender papules and nodules mainly on perigenital area, buttocks and right thigh.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Cutaneous malakoplakia in an HIV-positive patient

Savant¹,

Amladi²,

Kangle³

et al. 2007

Int J STD AIDS

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“…[126][127][128] Very nondescript red nodules or papules are present in the lower abdomen and the area of the groin, often around follicles. Escherichia coli is the most common causative organism, but S. aureus and Pseudomonas spp.…”

Section: Malacoplakiamentioning

confidence: 99%