Cutaneous Form of Polyarteritis Nodosa

A history of early investigation in polyarteritis nodosa

“…Necrotizing vasculitis confined to the skin, without systemic involvement, was described by Slinger and Starck in 1951 (37). These patients frequently have fever, joint pain, livedo, skin ulcers, and occasionally even the subcutaneous nodular lesions described first by Kussmaul and Maier.…”

Cutaneous Manifestations in Polyarteritis (Periarteritis) Nodosa

“…In this case, there were also some tender and raised hemorrhagic areas which became necrotic and ulcerated before death. Others who have recorded cases exhibiting recurrent crops of red, mostly tender nodules which might ulcerate, and/or livedoid reticular mani¬ festations on the skin, include Crosti, (1935), Carol and Prakken (1937), Dowling (1943), Miller and Daley (1946), Kimberly (1946), Oliver (1948), Ormsby (1948, Barber (1949), Slinger and Starck (1951), Lindgren and Lundmark (1956), Hellier (1957), and Rimbaud (1958). Lyell and Church, in 1954, reported three cases of polyarteritis nodosa in men, along with a review of the literature on the sub¬ ject.…”

Cutaneous Polyarteritis Nodosa: A Clinical and Histopathological Study of 20 Cases

“…On the other hand, other research workers (14)(15)(16)(17)(18)(19)(20) believe the disease to be only a stage or a early form of systemic PN, because there have been some cases (19)(20)(21)(22)(23)(24) that began with cutaneous manifestations and developed systemic PN at a later time. However, most of the previous reports (1-13) did not include longterm follow-up of the patients.…”