Cutaneous extramedullary plasmacytomas

Subcutaneous plasmacytomas with tropism to sites of previous trauma in a multiple myeloma patient treated with an autologous bone marrow transplant

“…Our patient is unique in terms of both the metastatic subcutaneous involvement of her disease and the strong tropism to sites of trauma. Furthermore, the lack of plasma cells in peripheral blood, the normal IgG level, and the absence of palpable adenopathy at the time of cutaneous presentation suggest that these lesions were not simply a late manifestation of fully disseminated disease [7].…”

Lupus vulgaris and cutaneous lymphoma

“…Extra-medullary plasmacytomas are rare (Bluefarb, 1955;Wuepper & Mackenzie, 1969;La Perriere, Wolf & Gellin, 1973) and the occurrence of primary cutaneous plasmacytomas is even more uncommon (Mikhail, Spindler & Kelly, 1970;Stankler & Davidson, 1974). These tumours are not yet included in the Kiel classification of lymphomas (Lennert et al, 1975;Burg & Braun-Falco, 1977) and occur, as in our patient, without skeletal changes, abnormal plasma proteins or Bence-Jones proteins in the urine.…”

Multiple extra-medullary plasmacytomas of the skin

“…Solitary and multiple extra-medullary plasmacytomas of the skin may occur in association with soft tissue plasmacytomas involving other organs (Hayes, Bennett & Heck, 1952;Switzer, Moseley & Cannon, 1950), or may form part of the picture of multiple myeloma (Zanca et al, 1964;Beevers, 1972;Haribhakti, 1966;Wuepper & MacKenzie, 1969). Multiple skin lesions may also be an expression of plasma cell leukaemia (Piney & Riach, 1931;Newman et ai, 1952).…”