1981
DOI: 10.1001/archderm.117.8.507
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Cutaneous cysticercosis treated with metrifonate

Abstract: Cutaneous cysticercosis in humans is an uncommon parasitic infestation. When few nodules are present, surgical excision is effective therapy. For multiple nodules, diverse forms of treatment have been employed. We describe herein a patient with myriad nodules of cysticercosis who showed dramatic improvement after two six-day courses of metrifonate (an organophosphorous compound) administered one month apart. These encouraging results could be of help to other patients, especially those with CNS involvement, al… Show more

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Cited by 10 publications
(7 citation statements)
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“…are based on the number and anatomical distribution of the cysticerci and the inflammatory response of the host [1,2]. The number of cysts varies from one (as in the case of our patient) to thousands [3]. Although the cysticerci may lodge in any body organs, they show a special preference for four tissues: subcutaneous and muscle tissue, the eye and the CNS [4].…”
Section: Discussionmentioning
confidence: 96%
“…are based on the number and anatomical distribution of the cysticerci and the inflammatory response of the host [1,2]. The number of cysts varies from one (as in the case of our patient) to thousands [3]. Although the cysticerci may lodge in any body organs, they show a special preference for four tissues: subcutaneous and muscle tissue, the eye and the CNS [4].…”
Section: Discussionmentioning
confidence: 96%
“…In the pig, the muscle tissue is particularly involved. Once in the muscle, the larvae develop into cysticerci [4]. The cystic structure contains a small, invaginated scolex and neck resembling the adult form.…”
Section: Discussionmentioning
confidence: 99%
“…The clinical course of cysticercosis depends on the number of cysts, the particular tissue infected, and the reaction of tissues to the organism [3]. The larvae may migrate to any organ and may remain viable for many years [4]. The organism most often invades the central nervous system, eye, subcutaneous tissue, skeletal muscle, and heart, but occasionally the lungs, liver, and kidneys may be affected.…”
Section: Discussionmentioning
confidence: 99%
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“…[4] They are rarely located in oral and perioral tissues, particularly in the muscles of mastication, muscle of the facial expression, the suprahyoid muscles, and the postcervical musculature and also as in the tongue, buccal mucosa, and lip. [567] Cysticercosis is a potentially fatal parasitic disease that rarely found in the maxillofacial region in humans. [8]…”
Section: Introductionmentioning
confidence: 99%