Current Perspectives on Management of Co-Morbid Depression in COPD

Norwood, Rachel; Balkissoon, Ronald

doi:10.1081/copd-200050740

Cited by 46 publications

(39 citation statements)

References 35 publications

(18 reference statements)

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“…Other studies that have demonstrated significant improvement have been limited by small numbers of participants [32]. In the absence of strong evidence-based guidance, an algorithm parallel to that used for non-COPD depressive patients is the best clinical strategy [33 ].…”

Section: Management Of Depression In Chronic Obstructive Pulmonary DImentioning

confidence: 99%

Prevalence and impact of depression in chronic obstructive pulmonary disease patients

Norwood

2006

Current Opinion in Pulmonary Medicine

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Section: Management Of Depression In Chronic Obstructive Pulmonary DImentioning

confidence: 99%

Prevalence and impact of depression in chronic obstructive pulmonary disease patients

Norwood

2006

Current Opinion in Pulmonary Medicine

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“…About 40% of patients with COPD are found to have depression, compared to a prevalence of about 15-20 % in the general population 14 . We found a prevalence of close to 90% of at least mild depression (as measured on the Hamilton depression scale) in patients admitted with COPD 15 .…”

Section: Introductionmentioning

confidence: 99%

Exercise alleviates depression related systemic inflammation in chronic obstructive pulmonary disease patients

2017

Afr H. Sci.

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Background: Depression is a highly prevalent co-morbidity in Chronic Obstructive Pulmonary Disease (COPD) which was shown to be associated with a worse course of disease, including reduced quality of life and increased symptoms burden, healthcare use, and even mortality. It has been speculated that systemic inflammation may play a role in the presence of depression. Currently, physical activity is an important lifestyle factor that has the potential to modify inflammatory cytokines and depression, however our understanding of how to use exercise effectively in COPD patients to alleviate depression related systemic inflammation is incomplete and has prompted our interest to identify the type and intensities of effective exercise. Objective: The aim of this study was to measure the changes in depression related systemic inflammation of aerobic exercise training in COPD patients in Jeddah area. Material and methods: Eighty patients with moderate severity of COPD participated in this study and were divided into two groups; the first group received aerobic exercise, whereas the second group received no exercise training for 12 weeks. Results:The mean values of tumor necrosis factor-alpha (TNF-α), interleukin-4 (IL-4), interleukin-6 (IL-6), C-reactive protein (CRP) and Beck Depression Inventory (BDI) scores were significantly decreased in in group (A) after treatments, but the changes in group (B) were not significant .Also, there were significant differences between mean levels of the investigated parameters in group (A) and group (B) at the end of the study. Conclusion: Aerobic exercise is an effective treatment policy to improve depression related to systemic inflammation in patients with chronic obstructive pulmonary disease.

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“…3 Patients with depression also characteristically make fewer attempts to improve their health. [4][5][6] Therefore, examining symptoms of depression is an important part of comprehensive COPD treatment.…”

Section: Introductionmentioning

confidence: 99%

Depression in Japanese Patients With Chronic Obstructive Pulmonary Disease: A Cross-Sectional Study

et al. 2012

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BACKGROUND: Some investigations have revealed an association between depression and physical measurements of COPD patients in North America and Europe, but few related studies have been performed in Asia. METHODS: In this cross-sectional study, 84 consecutive, stable outpatients with COPD (mean ؎ SD age 72.0 ؎ 9.0 y, percent-of-predicted FEV 1 46 ؎ 15%, 15 [17.9%] female) in a Japanese community hospital were recruited. "Probable depression" was defined as a score of > 6 on the short-form Geriatric Depression Scale (SF-GDS). Relationships among commonly used physical measurements, SF-GDS raw score, and probable depression were evaluated with the Spearman rank correlation test, multiple linear regression analysis, logistic regression analysis, and receiver operating characteristic curves. RESULTS: Thirty-two subjects (38.1%) had probable depression. Body mass index, obstruction, dyspnea, exercise capacity index, percent-ofpredicted FEV 1 , Modified Medical Research Council dyspnea score, 6-min walk distance, and S pO 2 had: simple correlations (r 0.42-0.60, P < .001 for all) with the SF-GDS raw score; partial correlations (r 0.25-0.51, P < .05 for all) with the SF-GDS raw score after adjusting for demographic and social factors; association with probable depression in the logistic regression analysis after adjusting for demographic and social factors (P < .05 for all); and areas under the receiver operating characteristic curve of 0.72؊0.84 (P < .001 for any) for probable depression. CONCLU-SIONS: Physical parameters were associated with depression in our Japanese COPD out-patients.

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Current Perspectives on Management of Co-Morbid Depression in COPD

Cited by 46 publications

References 35 publications

Prevalence and impact of depression in chronic obstructive pulmonary disease patients

Prevalence and impact of depression in chronic obstructive pulmonary disease patients

Exercise alleviates depression related systemic inflammation in chronic obstructive pulmonary disease patients

Depression in Japanese Patients With Chronic Obstructive Pulmonary Disease: A Cross-Sectional Study

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