Current approaches to the diagnosis and management of choroidal melanomas

Indigenous 125 I Brachytherapy Source for the Management of Intraocular Melanomas in India

“…The mode of metastasis is hematogenous for both histological subtypes, with the first site being the liver. 17,18 There are very few cases reported of spread of choroidal melanoma into the conjunctiva via regional lymphatics 19 and/or spread to the maxillofacial bones. 20 Every patient deserves a thoughtful individual assessment before therapeutic avenues are pursued.…”

Indigenous 125 I Brachytherapy Source for the Management of Intraocular Melanomas in India

“…The mode of metastasis is hematogenous for both histological subtypes, with the first site being the liver. 17,18 There are very few cases reported of spread of choroidal melanoma into the conjunctiva via regional lymphatics 19 and/or spread to the maxillofacial bones. 20 Every patient deserves a thoughtful individual assessment before therapeutic avenues are pursued.…”

Intra-ocular melanoma metastatic to an axillary lymph node: A case report

“…Most of the time a comprehensive eye exam alone by an Ophthalmologist can make the diagnosis [4]. Rarely an ultrasound or a biopsy is needed.…”

“…Epitheloid tumors are more likely to metastasize to distant sites than spindle cell variant (which is the histology in this case). The mode of metastasis is hematogenous for both histological subtypes, with the first site being the liver [3,4]. Tumor size is a significant prognostic factor for the development of metastatic disease [3-6].…”

Transvitreal retino‐choroidal biopsy of suspected malignant lesions of the choroid

“…Transscleral biopsy directly into the tumour has proved to be too hazardous because of the danger of extrascleral spread of tumour cells and the subsequent increased possibility of orbital recurrence followed by a graver prognosis (Jensen & Andersen 1959;Karcioglu et al 1985;Makley 1967;Sanders 1953;Shields 1977). Char et al (1989) used both biopsy directly through the sclera into the tumour and the transvitreal approach, and meticulously dried the area of needle perforation with neurosurgical pads.…”

Indigenous 125 I Brachytherapy Source for the Management of Intraocular Melanomas in India

“…The mode of metastasis is hematogenous for both histological subtypes, with the first site being the liver. 17,18 There are very few cases reported of spread of choroidal melanoma into the conjunctiva via regional lymphatics 19 and/or spread to the maxillofacial bones. 20 Every patient deserves a thoughtful individual assessment before therapeutic avenues are pursued.…”

Intra-ocular melanoma metastatic to an axillary lymph node: A case report

“…Most of the time a comprehensive eye exam alone by an Ophthalmologist can make the diagnosis [4]. Rarely an ultrasound or a biopsy is needed.…”

“…Epitheloid tumors are more likely to metastasize to distant sites than spindle cell variant (which is the histology in this case). The mode of metastasis is hematogenous for both histological subtypes, with the first site being the liver [3,4]. Tumor size is a significant prognostic factor for the development of metastatic disease [3-6].…”

Transvitreal retino‐choroidal biopsy of suspected malignant lesions of the choroid

“…Transscleral biopsy directly into the tumour has proved to be too hazardous because of the danger of extrascleral spread of tumour cells and the subsequent increased possibility of orbital recurrence followed by a graver prognosis (Jensen & Andersen 1959;Karcioglu et al 1985;Makley 1967;Sanders 1953;Shields 1977). Char et al (1989) used both biopsy directly through the sclera into the tumour and the transvitreal approach, and meticulously dried the area of needle perforation with neurosurgical pads.…”

Indigenous 125 I Brachytherapy Source for the Management of Intraocular Melanomas in India

“…The mode of metastasis is hematogenous for both histological subtypes, with the first site being the liver. 17,18 There are very few cases reported of spread of choroidal melanoma into the conjunctiva via regional lymphatics 19 and/or spread to the maxillofacial bones. 20 Every patient deserves a thoughtful individual assessment before therapeutic avenues are pursued.…”

Intra-ocular melanoma metastatic to an axillary lymph node: A case report

“…Most of the time a comprehensive eye exam alone by an Ophthalmologist can make the diagnosis [4]. Rarely an ultrasound or a biopsy is needed.…”

“…Epitheloid tumors are more likely to metastasize to distant sites than spindle cell variant (which is the histology in this case). The mode of metastasis is hematogenous for both histological subtypes, with the first site being the liver [3,4]. Tumor size is a significant prognostic factor for the development of metastatic disease [3-6].…”

Transvitreal retino‐choroidal biopsy of suspected malignant lesions of the choroid

“…Transscleral biopsy directly into the tumour has proved to be too hazardous because of the danger of extrascleral spread of tumour cells and the subsequent increased possibility of orbital recurrence followed by a graver prognosis (Jensen & Andersen 1959;Karcioglu et al 1985;Makley 1967;Sanders 1953;Shields 1977). Char et al (1989) used both biopsy directly through the sclera into the tumour and the transvitreal approach, and meticulously dried the area of needle perforation with neurosurgical pads.…”