CT of Cardiac Function

Savino, Giancarlo; Zwerner, Peter L.; Herzog, Christopher; Politi, Marco Angelo; Bonomo, Lorenzo; Costello, Philip; Schoepf, U. Joseph

doi:10.1097/rti.0b013e3180317433

Cited by 23 publications

(9 citation statements)

References 43 publications

(41 reference statements)

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“…First, imaging of the moving heart requires high temporal resolution to achieve an artifact-free display of myocardial contraction over the cardiac cycle [23]. High temporal resolution is needed to identify the proper image reconstruction windows for accurately measuring the LA volume and function.…”

Section: Discussionmentioning

confidence: 99%

Assessing the left atrial phasic volume and function with dual-source CT: comparison with 3T MRI

Wen

Zhang

et al. 2010

Int J Cardiovasc Imaging

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We wanted to assess the performance of dual-source CT (DSCT) for evaluating the left atrial volume and function and we compared this performance to that of the standard reference technique,cardiac cine MR (CMR). Fifty-one patients who were referred for CT coronary angiography were included in the study. Two were subsequently excluded for having un-analyzable MR images at the onset of left atrial contraction. For the remaining 49 patients, the DSCT data sets and FIESTA (fast imaging employing steady-state acquisition) cines of the vertical long axis covering the left atrium and the short axis covering the left ventricle were obtained on the same day. All the images were analyzed to obtain the maximal left atrial volume (LAVmax), the minimal left atrial volume (LAVmin), the left atrial volume just before left atrium contraction (LAVp), the left atrial reservoir volume (LARV), the left atrial ejection fraction (LAEF), the left atrial passive emptying volume (LAPV), the left atrial active emptying volume(LAAV), the left atrial conduit volume (LACV), the left ventricular end-diastolic volume (LVEDV), the left ventricular end-systolic volume (LVESV) and the left ventricular stroke volume (LVSV) by using 3D semi-segmentation software and Report Card 2.0 software, respectively, for the DSCT and CMR. All the parameters were normalized to the body surface area. Intermodality agreement was tested through linear regression and Bland-Altman analyses.Repeated measurements were performed to determine the interobserver variability. The DSCT measurements resulted in good correlation (r > 0.75) compared with those of CMR. However, DSCT slightly,but insignificantly overestimated the indexed LAVmax, LAVmin, LAVp, LARV, LAPV, LAAV and LACV, as reflected by biases of 1.2, 0.9, 1.1, 0.3, 0.1,0.2 and 0.4 ml/m(2), respectively. The LAEF was minimally, but insignificantly underestimated as reflected by a bias of -0.6% (P = ns). The variability of the DSCT measurements was lower than that of the CMR values. DSCT provides highly reliable and reproducible measurements of the left atrial phasic volume and function in patients who are referred for coronary CT imaging.

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Section: Discussionmentioning

confidence: 99%

Assessing the left atrial phasic volume and function with dual-source CT: comparison with 3T MRI

Wen

Zhang

et al. 2010

Int J Cardiovasc Imaging

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“…During ventricular systole, the true end-systolic volume is held for a period of only 80 to 200 ms. Temporal resolution lower than this decreases accuracy by impairing the ability to read wall motion and by increasing the likelihood that true end-systole and end-diastole will be missed, resulting in inaccurate EF measurements. Temporal resolution between 100 and 250 ms has been considered adequate to capture diastolic and systolic images, with the most recent generation of 64-slice MDCT able to reliably obtain a temporal resolution of 165 ms [2].…”

Section: Cardiac Mdctmentioning

confidence: 99%

Assessment of ventricular structure and function with multidetector CT and MRI

Sibley

Lima

2008

Curr Cardiol Rep

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Accurate, noninvasive assessment of ventricular function is fundamental to providing excellent care to patients with cardiovascular diseases. Three-dimensional imaging using cardiac magnetic resonance (CMR) permits the measurement of ventricular structure and function with such precision and accuracy that it now serves as the standard of reference for this purpose. Multidetector CT (MDCT) permits similar three-dimensional reconstruction and measurement of ventricular function. Available data indicate there is good agreement between MDCT and CMR measurements of ventricular function. Patients with cardiomyopathy and distorted ventricles stand to benefit the most from these techniques, particularly with the possibility of combined noninvasive angiography and systolic function assessment with MDCT.

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“…In routine clinical practice, functional analysis is most commonly done to evaluate the LV and aortic valve; if needed, the same principles and techn ique can be extrapolated for other cardiac chamber and mitral valve function assessment [7][8][9][10][11]. Precise eval uation of LV function is important for the diagnosis, therapy, and followup of patients with cardiac disease [58].…”

Section: Cardiac Functional Evaluationmentioning

confidence: 99%