1992
DOI: 10.1007/bf00448809
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Abstract: The study of the clinical isolates of Cryptococcus neoformans from 83 Brazilian patients with disseminated cryptococcosis showed that 75 were C. neoformans var. neoformans and 8 were var. gattii. Twenty-seven isolates were serotyped; all 19 var. neoformans were serotype A and all 8 var. gattii were serotype B. The correlation of the varieties of C. neoformans with the presence or not of hosts predisposing conditions to the mycosis showed that: (1) cryptococcosis caused by gattii variety occurred in 7 (58.3%) o… Show more

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Cited by 43 publications
(25 citation statements)
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“…neoformans, which has a strong association between the variety and the immune host status 36,85 . In Brazil, as occurs in other countries, cryptococcosis rates by gattii species in patients with AIDS are lower than the population, with other underlying diseases, or even without immunodepression, a data consistent with the worldwide literature 6,13,26,74,77,78,79,83,97 . PAULA et al 69 in a study of the cryptococcosis agent, in 40 cases not associated to infection by HIV, demonstrated the proportion of gattii of about 33% while in AIDS patients this rate is below 1% 51,58,62 .…”
supporting
confidence: 82%
“…neoformans, which has a strong association between the variety and the immune host status 36,85 . In Brazil, as occurs in other countries, cryptococcosis rates by gattii species in patients with AIDS are lower than the population, with other underlying diseases, or even without immunodepression, a data consistent with the worldwide literature 6,13,26,74,77,78,79,83,97 . PAULA et al 69 in a study of the cryptococcosis agent, in 40 cases not associated to infection by HIV, demonstrated the proportion of gattii of about 33% while in AIDS patients this rate is below 1% 51,58,62 .…”
supporting
confidence: 82%
“…neoformans (serotypes A, actually C. grubii) and var. gattii (serotype B) were the common causative agents of cryptococcosis and the number of cases increased after the advent of AIDS 2,14,21,22 . As clearly shown in Tables 1 and 2, our results support the above observations, and furthermore demonstrate that serotype A is predominant in the C. neoformans isolates from AIDS patients in São Paulo and surrounding areas.…”
Section: Discussionmentioning
confidence: 99%
“…neoformans is isolated rather frequently in Europe and South America 17 . Thus, it is of interest to determine the varieties and serotypes of C. neoformans isolates from patients in Brazil where all the varieties are endemic 2,14,15,18,20,21,22 .…”
Section: Introductionmentioning
confidence: 99%
“…neoformans (serotype D) among clinical isolates has ranged from 0 to 100% depending on the region of the world. In Brazil, the prevalence of serotype D is very low (29) …”
Section: Introductionmentioning
confidence: 99%