Cryptococcosis

Cryptococcosis with Cutaneous Manifestations Treated with 5-Fluorocytosine

“…Infrequently, a chronic infection is established which gives rise to occasional flares of systemic involvement. The second type of disease is associated with Hodgkin's disease, lymphoma [3], leukemia [ 22]: debilitating disease -diabetes mellitus [10]; prolonged use of systemic cor ticosteroids [17]; immunological diseases -sarcoidosis [I], systemic lupus erythematosus, and multiple myeloma [18], In these cases the host defense is minimal and inadequate, and the disease readily spreads to almost all or gans. The case described in this report was probably caused by inhalation of the fungus, and developed systemic involvement without underlying disease.…”

“…Cutaneous manifestation usually occurs in about 10-20% of the cases [19], The skin lesions present as papules, nodules, acneiform pustules, or ab scesses with ulceration and crusting with time, but occasionally skin lesions present as vesicles, purpura or a mass [3,15,18], The predilection site is usu ally the face and extremities. Our case presented typical skin findings.…”

“…The skin lesions present as papules, nodules and acneiform pustules, occasionally with ulceration and crusting [3],…”