Cryotherapy of common viral warts at intervals of 1, 2 and 3 weeks

Bourke, John; Berth‐Jones, J.; Hutchinson, P.E.

doi:10.1111/j.1365-2133.1995.tb08678.x

Cited by 84 publications

(69 citation statements)

References 2 publications

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“…[34][35][36][37] However, the cure rates after 6 months are often similar, suggesting that clearance may in fact depend on the total number of treatments given. Only one randomized trial has explored the total number of treatments, and even this trial was not ideally designed to answer this question.…”

Section: 29mentioning

confidence: 99%

British Association of Dermatologists' guidelines for the management of cutaneous warts 2014

et al. 2014

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Section: 29mentioning

confidence: 99%

British Association of Dermatologists' guidelines for the management of cutaneous warts 2014

et al. 2014

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“…There are many studies that compared the efficacy of cryotherapy with other modalities and assessed cure rates for cryotherapy of viral warts (Table 5) 3,4,[8][9][10][11][12][13][14][15][16][17][18][19] . These studies show cure rates ranging from 43% to 83%.…”

Section: Discussionmentioning

confidence: 99%

“…One is dividing them as common warts, palmoplantar warts, and periungual warts. The other is dividing them by location as hand only, foot only, and both hands and feet [8][9][10][11][12] . We grouped the subtype as hand only, foot only, and both hands and feet, because the first therapy for hand-foot warts is usually cryotherapy, and there is no overlap between subtypes.…”

Section: Discussionmentioning

confidence: 99%

A Two-week Interval Is Better Than a Three-week Interval for Reducing the Recurrence Rate of Hand-foot Viral Warts after Cryotherapy: A Retrospective Review of 560 Hand-foot Viral Warts Patients

et al. 2011

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Background: Viral warts are a common infectious disease and liquid nitrogen cryotherapy is one of the most common methods for treatment of these warts. Hand-foot viral warts frequently recur and reduce quality of life as well. Objective: To find the ideal treatment interval between cryotherapy sessions that can influence not only the cure rate but also the recurrence rate for hand-foot viral warts. Methods: A retrospective study was designed to compare a 2 week interval and a 3 week interval between cryotherapy sessions on hand-foot viral warts with respect to cure rate, recurrence rate, treatment number, duration of treatment, mean time to recurrence and adverse events. Results: A total of 560 patients were enrolled. The overall cure rate was 75.7% and the recurrence rate was 19.6%. The mean time to recurrence was 7.8 months (range 1∼26 months). For the 2-week and 3-week groups, cure rates were, respectively, 76.6% (196) and 75.0% (228); recurrence rates were 13.3% (26) and 25.0% (57). The mean time to recurrence was 9.8 months and 6.9 months, respectively. Adverse events were not statistically different. Conclusion: We suggested that 2-week cryotherapy is optimal not only because of the rapid cure but also because of the lower recurrence rate and similar adverse events. (Ann Dermatol 23(1) 53∼60, 2011)

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“…100 In a study of the frequency of wart cryotherapy and the efficacy of cure at 1, 2 or 3 week intervals, the percentage cured was related to the number of treatments but was independent of the interval between treatments. 101 Optimal treatment may be every 2 weeks, as it achieves a faster cure without affecting department workload, especially for patients who may desire a quicker cure before a forthcoming event. 101 In an assessment of 16 cryotherapy trials, most compared different regimens instead of comparing cryotherapy to other treatments or placebo.…”

Section: Cryotherapymentioning

confidence: 99%

An Armamentarium of Wart Treatments

Lipke¹

2006

Clinical Medicine & Research

282

295

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Patients and clinicians experience the frustration of cutaneous viral warts caused by infection with the human papilloma virus (HPV).Warts appear in various forms on different sites of the body and include common warts (verruca vulgaris), plane or flat warts, myrmecia, plantar warts, coalesced mosaic warts, filiform warts, periungual warts, anogenital warts (venereal or condyloma acuminata), oral warts and respiratory papillomas. Cervical infection with HPV is now known to cause cervical cancer if untreated. A review of the medical literature reveals a huge armamentarium of wart monotherapies and combination therapies. Official evidence-based guidelines exist for the treatment of warts, but very few of the reported treatments have been tested by rigorous blinded, randomized controlled trials.Therefore, official recommendations do not often include treatments with reportedly high success rates, but they should not be ignored when considering treatment options. It is the purpose of this review to provide a comprehensive overview of the wart treatment literature to expand awareness of the options available to practitioners faced with patients presenting with problematic warts. Warts of the genital tract carry a much more ominous and pernicious threat for women in particular. It has been estimated that up to 70% of sexually active women become infected during their lifetime with human papillomavirus (HPV), the infective agent that causes warts. 3-5 A causal role for HPV infections in cervical cancer has been documented beyond reasonable doubt. HPV DNA is present in virtually all cervical cancer cases worldwide, with it being detected in 99.7% of an international series of cervical cancers by genetic amplification techniques and in 100% of cases as confirmed by histological review. 6,7 Cervical cancer is the most frequent common cancer in developing countries and the second most common cancer in women worldwide. 3 The association between HPV infection and cervical cancer is so strong that HPV is now considered the first positive cause of any human cancer ever identified. 3This raises the level of concerns over HPV prevention, screening and treatment from that of a nuisance condition to that of a major public health concern. Attention is beginning to focus on the viral factors that determine persistence and neoplastic progression to cancer and the possible role of HPV in other nongenital cancers (e.g., skin, upper aerodigestive tract). [8][9][10][11][12][13][14][15][16][17] Patients with warts seek advice from general practitioners, pharmacists, naturopaths, allied health professionals, family or friends, dermatologists, gynecologists, obstetricians and pediatricians for treatment and may present with recalcitrant warts that have been previously treated with anything from folk remedies to hypnosis to over-the-counter medications to more aggressive clinic-based treatments. Unfortunately, even with years of medical literature on this subject, high-quality, level I evidence for the efficacy of almost all treatments is no...

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Cryotherapy of common viral warts at intervals of 1, 2 and 3 weeks

Cited by 84 publications

References 2 publications

British Association of Dermatologists' guidelines for the management of cutaneous warts 2014

British Association of Dermatologists' guidelines for the management of cutaneous warts 2014

A Two-week Interval Is Better Than a Three-week Interval for Reducing the Recurrence Rate of Hand-foot Viral Warts after Cryotherapy: A Retrospective Review of 560 Hand-foot Viral Warts Patients

An Armamentarium of Wart Treatments

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