Cryolite glass prosthetic eyes—the response of the anophthalmic socket

Rokohl, Alexander C.; Adler, Werner; Koch, Konrad R.; Mor, Joel M.; Jia, Renbing; Trester, Marc; Pine, Nicola S.; Pine, Keith R.; Heindl, Ludwig M.

doi:10.1007/s00417-019-04395-y

Cited by 23 publications

(30 citation statements)

References 23 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…1 Patients with higher PHQ-9 score also had higher GAD-7 scores insights into quality of life-affecting factors such as general health status, appearance-related distress, appearance-related social function, and vision-related quality of life. The demographic data of the 295 consecutive enrolled patients was very similar to the data of previous studies and was therefore representative for the ordinary anophthalmic population in Germany quite well [3,4,13]. However, limitations of this study include the rather high proportion of patients with enucleation in relation to eviscerations or not operated patients as well as the design as a monocenter study conducted at an ocularistic institute.…”

Section: Discussionsupporting

confidence: 52%

“…The 7-item generalized anxiety disorder (GAD-7) scale is a validated, reliable, and efficient measurement tool for GAD screening and assessing its severity in clinical practice and in research [34]. The GAD-7 scale classifies 4 levels of anxiety severity: none (0-4), mild (5-9), moderate (10)(11)(12)(13)(14), and severe (15)(16)(17)(18)(19)(20)(21) [34].…”

Section: Methodsmentioning

confidence: 99%

“…Most psychological studies regarding prosthetic eye wearers focused on concerns of anophthalmic patients or quality of life-affecting issues in this ordinary population [1][2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18][19][20]. The eye loss itself, a potential malignant eye disease, the health of the fellow eye, potential discharge at the anophthalmic socket, dry socket symptoms, altered visual perception, and changes of the appearance have been already reported as relevant life-affecting and distress-causing factors [1-7, 13-18, 21-23].…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Anxiety and depression in patients wearing prosthetic eyes

Heindl

Trester²,

Guo

et al. 2020

Graefes Arch Clin Exp Ophthalmol

Self Cite

View full text Add to dashboard Cite

Purpose To investigate anxiety and depression levels in prosthetic eye-wearing patients using standardized psychometric instruments, to define factors associated with these psychological diseases, and to identify a potential healthcare gap. Methods A total of 295 prosthetic eye wearers were screened using the 7-item generalized anxiety disorder scale (GAD-7) and the 9-item patient health questionnaire (PHQ-9). Scores of GAD-7 and PHQ-9 were correlated with scores of general physical and mental health functioning, vision-related quality of life, appearance-related distress, appearance-related social function, and further biosocial factors. Results Five patients (2%) had a pre-diagnosed anxiety disorder, and 20 patients (7%) had a pre-diagnosed depression. However, our screening revealed 26 patients (9%) with anxiety symptoms, 31 patients (11%) with depression symptoms, and 40 patients (14%) suffering from both anxiety and depression symptoms. This underdiagnosing for both anxiety and depression disorders was significant (p < 0.001, respectively). Higher GAD-7 scores were significantly associated with higher PHQ-9 scores, lower appearance-related social function, lower mental health functioning, and female gender (p ≤ 0.021, respectively). Higher PHQ-9 scores were significantly associated with lower physical and mental health functioning, higher educational degree, and nontraumatic eye loss (p ≤ 0.038, respectively). Conclusions Anxiety and depression disorders seem to be underdiagnosed in prosthetic eye wearers and to have higher incidence compared with the general population. Therefore, a psychometric screening should be routinely implemented in the clinical care. For a successful long-term rehabilitation, integrated care by a multidisciplinary team including ophthalmic plastic surgeons, ophthalmologists, ocularists, general practitioners, and psychologists is essential.

show abstract

Section: Discussionsupporting

confidence: 52%

Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Anxiety and depression in patients wearing prosthetic eyes

Heindl

Trester²,

Guo

et al. 2020

Graefes Arch Clin Exp Ophthalmol

Self Cite

View full text Add to dashboard Cite

show abstract

“…A common condition of ocular discomfort in a long-standing patient with ocular prosthesis is giant papillary conjunctivitis, due to a prolonged mechanical irritation and the immunologic reaction of the ocular surface [11,12]. Rokohl et al documented a relationship between the discharge severity of prosthetic eyewear with conjunctival inflammation, higher cleaning frequency and less hand washing before handling [13]. The role of reduced tear production was documented in previous studies.…”

Section: Discussionmentioning

confidence: 96%

Prevalence of Meibomian Gland Dysfunction and Its Effect on Quality of Life and Ocular Discomfort in Patients with Prosthetic Eyes

Meduri

Frisina

Rechichi³

et al. 2020

Prosthesis

View full text Add to dashboard Cite

Purpose: To evaluate the influence of ocular discomfort and meibomian gland dysfunction (MGD) on quality of life in patients with an ocular prosthesis. Methods: a prospective analysis was conducted on 18 patients with a unilateral ocular prosthesis. Evaluation of ocular discomfort symptoms, lid margin abnormalities (LMA), meibomian gland expression, meibography and a psychometric evaluation using the National Eye Institute Visual Function Questionnaire (NEI VFQ), Facial Appearance subscale of the Negative Physical Self Scale (NPSS-F), Hospital Anxiety and Depression Scale (HADS) and the DAS24 to evaluate anxiety and depression. Results: the statistically significant differences observed between normal and prosthetic eyes related to ocular symptoms and the meibography score (p = 0.0003). A negative correlation was reported between NEI VFQ score and meibography score (r = −0.509; p-value = 0.022). A positive correlation was detected with NPSS (r = 0.75; p-value < 0.0001), anxiety HADS score (r = 0.912; p-value = 0.001) and depression HADS score (r = 0.870; p-value > 0.0001). Conclusion: MGD represents the most common cause of evaporative dry eye disease, due to the reduction of the thickness of the lipid layer of the tear film. The occurrence of MGD in patients with prosthetic eyes is very common. Anxiety and depression were correlated to ocular discomfort and MGD, and this could affect the quality of life in patients with an ocular prosthesis.

show abstract

“…Inflammatory response of the sockets was mainly noticed together with simultaneous cold symptoms. Rokohl et al (2019b) reported that conjunctival inflammation among their cryolite glass prosthetic eye wearers was associated with higher frequency of cleaning of the prosthesis and lower frequency of hand washing before removal. The conformers and prosthesis are not taken out for cleaning except if necessary during a cold.…”

Section: Discussionmentioning

confidence: 99%

Children and young adults with anophthalmia and microphthalmia: Diagnosis and Management

Najim

Topa

Jugård

et al. 2020

Acta Ophthalmologica

View full text Add to dashboard Cite

Purpose Congenital anophthalmia (A) and microphthalmia (M) are rare developmental defects, which could be isolated or syndromic. Our objective was to describe a cohort of children and young adults with A/M treated with ocular prosthesis, emphasizing clinical features, diagnosis, treatment, and follow‐up. Methods Eighteen individuals (10 female) with unilateral A (n = 3) and M (n = 15) with a mean age of 9.5 years (range 0.8–31.8) and treated with ocular prosthesis were included. Data on medical history, clinical examinations and management of ocular prosthesis were collected. Genetic screening with microarray and whole‐exome sequencing targeting 121 A/M‐related genes was performed. Results A/M appeared isolated (seven cases) or as part of a syndromic condition (11 cases). In 4/16 patients, mutations were detected in TFAP2A, CHD7, FOXE3 and BCOR‐genes. In one patient, a possibly causal microdeletion 10q11 was shown. Associated ocular anomalies such as cataract and cysts were found in 16 (89%) of the A/M eyes, and in nine (50%) ophthalmological findings were found in the fellow eyes. The median ages at which the conformer and ocular prosthesis first were initiated were 7.8 months and 1.5 years. 16/17 patients fulfilled satisfactory orbital growth and cosmetic results when treated with ocular prosthesis from an early age. Conclusion Based upon our findings, a multidisciplinary approach, including genetic assessment, is necessary to cover all aspects of A/M. Imaging, ultrasound and visual evoked potentials should be included. Early management is crucial for the outcome, in terms of non‐ocular findings, vision in the fellow eye, and for facial cosmetic development.

show abstract

Cryolite glass prosthetic eyes—the response of the anophthalmic socket

Cited by 23 publications

References 23 publications

Anxiety and depression in patients wearing prosthetic eyes

Anxiety and depression in patients wearing prosthetic eyes

Prevalence of Meibomian Gland Dysfunction and Its Effect on Quality of Life and Ocular Discomfort in Patients with Prosthetic Eyes

Children and young adults with anophthalmia and microphthalmia: Diagnosis and Management

Contact Info

Product

Resources

About