J. Neurosci. Res. volume 86, issue 1, P27-34 2007 DOI: 10.1002/jnr.21454 View full text
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Hong Liao, Wenhui Huang, Rui Niu, Lixin Sun, Luyong Zhang

Abstract: Mounting evidence has demonstrated that the microenvironment of stem/progenitor cells plays an important role in their proliferation and commitment to their fate. However, it remains unclear how all elements, such as astrocytes, microglia, extracellular matrix molecules, soluble factors, and their cross-talk interactions in the microenvironments, affect neural stem/progenitor cell fate. This work explored the influences of cross-talk between Tenascin-R (TN-R) and microglia on neural stem/progenitor cell prolif…

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