Cromolyn Effects on Vernal Keratoconjunctivitis in Children

Clinical Trial of Topical Disodium Chromoglycate in Vernal Keratoconjunctivitis

“…Their results were contradictory. Easty et al [1972a, b] and Tabbara and Arafat [1977] found con trary to Hyams et al [1975], that the drug has a significant therapeutic effect. Our re sults confirm that DSCG has a significant therapeutic effect, specially on the nasal changes, clinical symptoms and corneal re actions.…”

Clinical Trial of Topical Disodium Chromoglycate in Vernal Keratoconjunctivitis

“…Their results were contradictory. Easty et al [1972a, b] and Tabbara and Arafat [1977] found con trary to Hyams et al [1975], that the drug has a significant therapeutic effect. Our re sults confirm that DSCG has a significant therapeutic effect, specially on the nasal changes, clinical symptoms and corneal re actions.…”

Topical indomethacin for vernal keratoconjunctivitis

“…After a washout period of 7 days, 1% indomethacin eyedrops (Flamisol eyedrops containing 0.002% phenylmercuric nitrate as preservative) were instilled 3 times a day. The subjective and objective evaluation was carried out after detailed questioning and thorough ocular examination including fluorescein staining and slit lamp biomicroscopy, according to modified criteria of Tabbora & Arafat (1977) (Table 1). Follow-up evaluation was done on the second day and weekly for 5 weeks, and depending upon the total score of the patient, the clinical response was graded as shown in Table 2.…”

Vernal keratoconjunctivitis: A severe allergic eye disease with remodeling changes

“…Interest in applying cromolyn (DSCG) eye solution for VKC treatment started as early as the late 1970s. Both 2% and 4% DSCG solution were found to be superior to placebo in reducing signs and symptoms of VKC (12,(47)(48)(49)(50). However, symptoms in severe VKC often persisted even after prolonged use of DSCG (50).…”

Clinical Trial of Topical Disodium Chromoglycate in Vernal Keratoconjunctivitis

“…Their results were contradictory. Easty et al [1972a, b] and Tabbara and Arafat [1977] found con trary to Hyams et al [1975], that the drug has a significant therapeutic effect. Our re sults confirm that DSCG has a significant therapeutic effect, specially on the nasal changes, clinical symptoms and corneal re actions.…”

Topical indomethacin for vernal keratoconjunctivitis

“…After a washout period of 7 days, 1% indomethacin eyedrops (Flamisol eyedrops containing 0.002% phenylmercuric nitrate as preservative) were instilled 3 times a day. The subjective and objective evaluation was carried out after detailed questioning and thorough ocular examination including fluorescein staining and slit lamp biomicroscopy, according to modified criteria of Tabbora & Arafat (1977) (Table 1). Follow-up evaluation was done on the second day and weekly for 5 weeks, and depending upon the total score of the patient, the clinical response was graded as shown in Table 2.…”

Vernal keratoconjunctivitis: A severe allergic eye disease with remodeling changes

“…Interest in applying cromolyn (DSCG) eye solution for VKC treatment started as early as the late 1970s. Both 2% and 4% DSCG solution were found to be superior to placebo in reducing signs and symptoms of VKC (12,(47)(48)(49)(50). However, symptoms in severe VKC often persisted even after prolonged use of DSCG (50).…”

Clinical Trial of Topical Disodium Chromoglycate in Vernal Keratoconjunctivitis

“…Their results were contradictory. Easty et al [1972a, b] and Tabbara and Arafat [1977] found con trary to Hyams et al [1975], that the drug has a significant therapeutic effect. Our re sults confirm that DSCG has a significant therapeutic effect, specially on the nasal changes, clinical symptoms and corneal re actions.…”

Topical indomethacin for vernal keratoconjunctivitis

“…After a washout period of 7 days, 1% indomethacin eyedrops (Flamisol eyedrops containing 0.002% phenylmercuric nitrate as preservative) were instilled 3 times a day. The subjective and objective evaluation was carried out after detailed questioning and thorough ocular examination including fluorescein staining and slit lamp biomicroscopy, according to modified criteria of Tabbora & Arafat (1977) (Table 1). Follow-up evaluation was done on the second day and weekly for 5 weeks, and depending upon the total score of the patient, the clinical response was graded as shown in Table 2.…”

Vernal keratoconjunctivitis: A severe allergic eye disease with remodeling changes

“…Interest in applying cromolyn (DSCG) eye solution for VKC treatment started as early as the late 1970s. Both 2% and 4% DSCG solution were found to be superior to placebo in reducing signs and symptoms of VKC (12,(47)(48)(49)(50). However, symptoms in severe VKC often persisted even after prolonged use of DSCG (50).…”