2011
DOI: 10.5581/1516-8484.20120016
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Craniofacial bone abnormalities and malocclusion in individuals with sickle cell anemia

Abstract: This study aims to critically review the literature in respect to craniofacial bone abnormalities and malocclusion in sickle cell anemia individuals. The Bireme and Pubmed electronic databases were searched using the following keywords: malocclusion, maxillofacial abnormalities, and Angle Class I, Class II and lass III malocclusions combined with sickle cell anemia. The search was limited to publications in English, Spanish or Portuguese with review articles and clinical cases being excluded from this study. T… Show more

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Cited by 23 publications
(18 citation statements)
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“…25 Likewise, the severity of children's malocclusion was associated with a negative impact Dental malocclusion may cause functional disorders or disabilities other than aesthetic discomfort. 29, 30 It stands to reason that parents of children with SCD can also perceive this impact. Despite the negative impact of malocclusions in adolescents, when evaluating specific items of the FIS, the final multivariate model showed that only an increase in DMFT produced a negative impact on the parents' QoL.…”
Section: Discussionmentioning
confidence: 99%
“…25 Likewise, the severity of children's malocclusion was associated with a negative impact Dental malocclusion may cause functional disorders or disabilities other than aesthetic discomfort. 29, 30 It stands to reason that parents of children with SCD can also perceive this impact. Despite the negative impact of malocclusions in adolescents, when evaluating specific items of the FIS, the final multivariate model showed that only an increase in DMFT produced a negative impact on the parents' QoL.…”
Section: Discussionmentioning
confidence: 99%
“…Most studies on this issue have been performed with small samples, using descriptive, case report, or crosssectional designs, and with no control for confounding factors, on samples that grouped the deciduous and mixed dentitions, and without considering the severity of MO. 5 Thus, the objective of this study was to assess the possible associations between SCA and the severity of MO. The null hypothesis tested was that there is no difference in the severity of MO between patients with SCA and control subjects.…”
Section: Introductionmentioning
confidence: 99%
“…In some studies dental abnormalities were also relatively common in control subjects without SCD and in one study the prevalence was higher in controls [10]. Thus the pathophysiology of the association between SCD and dental complications is not clear and the scientific proof that SCD causes malocclusion is insufficient [26,27].…”
Section: Malocclusionmentioning
confidence: 99%