Cp∗Co(III)-catalyzed direct functionalization of aromatic C–H bonds with α-diazomalonates

Liu, Xu‐Ge; Zhang, Shang‐Shi; Wu, Jia‐Qiang; Li, Qingjiang; Wang, Honggen

doi:10.1016/j.tetlet.2015.05.025

Cited by 101 publications

(40 citation statements)

References 71 publications

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“…The Cp*Co III species was used as a transition metal and a Lewis acid catalyst to facilitate C−H activation and sequential cyclization in this transformation. At the same time, Wang and co‐workers also realized [Cp*Co III (CO) I 2 ]‐catalyzed C−H alkylation with diazo compounds …”

Section: C−h Activation/functionalizations Catalyzed By Using Cp*coimentioning

confidence: 98%

High‐Valent‐Cobalt‐Catalyzed C−H Functionalization Based on Concerted Metalation–Deprotonation and Single‐Electron‐Transfer Mechanisms

et al. 2016

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C−H functionalization has been established as a powerful strategy for the commercial construction of organic molecules. This review encompasses the most recent advances in C−H activation catalyzed by earth‐abundant cobalt complexes, involving two types of fundamental reaction paths, that is, the concerted metalation–deprotonation (CMD) path associated with non‐oxidative C−H activation and the intermolecular single‐electron‐transfer (SET) path. Transformations catalyzed by high‐valent cobalt based on the two mechanisms and used in organic syntheses, including those involving C−C and C−X (X=O and N) bond formation, are herein presented.

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Section: C−h Activation/functionalizations Catalyzed By Using Cp*coimentioning

confidence: 98%

High‐Valent‐Cobalt‐Catalyzed C−H Functionalization Based on Concerted Metalation–Deprotonation and Single‐Electron‐Transfer Mechanisms

et al. 2016

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“…23a Very recently, we have developed a Cp*Co(III)-catalyzed aromatic C−H coupling with diazomalonates. 8 Herein, we would like to disclose our realization of a Cp*Co(III)-catalyzed annulation reaction of 2-alkenylphenols with CO (balloon pressure) under remarkably mild conditions (Scheme 1d).…”

mentioning

confidence: 99%

Cp*Co(III)-Catalyzed Annulations of 2-Alkenylphenols with CO: Mild Access to Coumarin Derivatives

et al. 2015

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Cp*Co(III)-catalyzed annulations of 2-alkenylphenols with CO for the synthesis of coumarin derivatives have been developed. The reaction features mild reaction conditions, broad substrate scope, and good functional group tolerance. Preliminary mechanistic studies were conducted, suggesting that C-H activation is the turnover limiting step. Furthermore, the efficiency of this reaction was demonstrated by the rapid total synthesis of three natural products herniarin, xanthyletin, and seselin.

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“…As part of an ongoing research program on the C-H functionalization of indoles [32][33][34][35], we describe herein a facile and mild Rh(III)-catalyzed highly selectively direct C-H alkylation of indoles with diazo compounds. During the preparation of this manuscript, a similar work was published by Wang and coworkers [36].…”

Section: Introductionmentioning

confidence: 78%

Rh(III)-Catalyzed, Highly Selectively Direct C–H Alkylation of Indoles with Diazo Compounds

Wan

Xing

et al. 2016

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Cp∗Co(III)-catalyzed direct functionalization of aromatic C–H bonds with α-diazomalonates

Cited by 101 publications

References 71 publications

High‐Valent‐Cobalt‐Catalyzed C−H Functionalization Based on Concerted Metalation–Deprotonation and Single‐Electron‐Transfer Mechanisms

High‐Valent‐Cobalt‐Catalyzed C−H Functionalization Based on Concerted Metalation–Deprotonation and Single‐Electron‐Transfer Mechanisms

Cp*Co(III)-Catalyzed Annulations of 2-Alkenylphenols with CO: Mild Access to Coumarin Derivatives

Rh(III)-Catalyzed, Highly Selectively Direct C–H Alkylation of Indoles with Diazo Compounds

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