COVID-19 epidemic: a special focus on diagnosis, complications, and management

Ai, Leilei; Jiang, Liyu; Xu, Zhifei; Hu, Yan; Luo, Peihua; He, Qiaojun

doi:10.1080/17512433.2020.1821651

Cited by 2 publications

(3 citation statements)

References 79 publications

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“…Computed tomography has great sensitivity for detecting patterns related to COVID-19, but a low specificity therefore is recommended to be used in combination with a more specific diagnostic method ( 34 – 36 ). In a study on 1,014 patients in Wuhan who underwent RT-PCR and chest CT for COVID-19 assessment, a positive COVID-19 chest CT had a sensitivity of 97% using RT-PCR as a reference; however, the specificity was only 25% ( 14 ). CT, despite not being a completely reliable diagnostic tool, is useful in determining the severity of COVID-19 in clinical practice ( 37 ).…”

Section: Discussionmentioning

confidence: 99%

“…COVID-19 related-pneumonia is a complication of moderate and severe forms of the disease and are characterized by a higher incidence of bilateral infiltrates, mainly ground-glass opacities and consolidations on chest computed tomography (chest CT) ( 10 , 11 ). CT scan findings are often used for diagnostic confirmation through protocols such as COVID-19 Reporting and Data System (CO-RADS), which classifies the image findings in CO-RADS categories in accordance with their characteristics, has a good application for triage in symptomatic individuals ( 12 , 13 ), and helps to monitor the progression of the disease ( 14 , 15 ).…”

Section: Introductionmentioning

confidence: 99%

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Chest Computed Tomography Is an Efficient Method for Initial Diagnosis of COVID-19: An Observational Study

et al. 2022

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Coronavirus disease (COVID-19) is an infectious disease that can lead to pneumonia, pulmonary oedema, acute respiratory distress syndrome, multiple organ and system dysfunction, and death. This study aimed to verify the efficacy of chest computed tomography (CT) for the initial diagnosis of COVID-19. This observational, retrospective, cross-sectional study included 259 individuals who underwent clinical evaluation, blood collection, chest CT, and a reverse transcription polymerase chain reaction (RT-PCR) diagnostic test for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) during their course of treatment at a reference hospital in Belém, Pará, Brazil between April and June 2020. Inclusion criteria were flu-like symptoms in adults of both sexes. Individuals with an inconclusive COVID-19 molecular test or who had artifacts in the chest CT images were excluded. Parametric data were analyzed using Student-t-test and non-parametric data were analyzed using average test and Fisher exact test. Participants were divided into two groups: Group 1 (COVID-19 positive), n = 211 (124 males, 87 females), 51.8 ± 17.9 years old and Group 2 (COVID-19 negative), n = 48 (22 males, 26 females), 47.6 ± 18.6 years old. Most frequent symptoms were cough [Group 1 n = 199 (94%)/Group 2 n = 46 (95%)], fever [Group 1 n = 154 (72%)/Group 2 n = 28 (58%)], myalgia [Group 1 n = 172 (81%)/Group 2 n = 38 (79%)], dyspnoea [Group 1 n = 169 (80%) / Group 2 n = 37 (77%)], headache [Group 1 n = 163 (77%)/Group 2 n = 32 (66%)], and anosmia [Group 1 n = 154 (73%)/Group 2 n = 29 (60%)]. Group 1 had a higher proportion of ground-glass opacity [Group 1 n = 175 (83%)/Group 2 n = 24 (50%), 0.00], vascular enhancement sign [Group 1 n = 128 (60%)/Group 2 n = 15 (31%), 0.00], septal thickening [Group 1 n = 99 (47%)/Group 2 n = 13 (27%), 0.01], crazy-paving pattern [Group 1 n = 98 (46%) / Group 2 n = 13 (27%), 0.01], consolidations [Group 1 n = 92 (43%)/Group 2 n = 8 (16%), 0.00], and CO-RADS 4 and 5 [Group 1 n = 163 (77.25%)/Group 2 n = 24 (50%), 0.00] categories in chest CT. Chest CT, when available, was found to be an efficient method for the initial diagnosis and better management of individuals with COVID-19.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Chest Computed Tomography Is an Efficient Method for Initial Diagnosis of COVID-19: An Observational Study

et al. 2022

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“…The involvement of the gastrointestinal system (by anorexia, nausea, vomiting) and urinary system (for instance, renal impairment) has been also stated about the complications of COVID-19. Septic shock, miscarriage, and premature delivery are also other complications [ 9 ]. Thus, the effects of coronaviruses are not limited to the respiratory tract.…”

Section: Covid-19 Infectionmentioning

confidence: 99%