2021
DOI: 10.1371/journal.pone.0246590
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Abstract: Introduction COVID-19 complications can include neurological, psychiatric, psychological, and psychosocial impairments. Little is known on the consequences of SARS-COV-2 on cognitive functions of patients in the sub-acute phase of the disease. We aimed to investigate the impact of COVID-19 on cognitive functions of patients admitted to the COVID-19 Rehabilitation Unit of the San Raffaele Hospital (Milan, Italy). Material and methods 87 patients admitted to the COVID-19 Rehabilitation Unit from March 27th to … Show more

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Cited by 186 publications
(246 citation statements)
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“…Among 77 COVID-19 patients undergoing acute inpatient rehabilitation, 80.5% of patients demonstrated cognitive impairment, the majority of whom had mild deficits. This number is consistent with studies using neuropsychological assessments to evaluate cognition in hospitalized COVID-19 patients 5-6 and expands on these findings with a larger sample than previous studies. Consistent with the literature, delirium during acute hospitalization is associated with greater cognitive impairment at admission 10 , emphasizing the importance of early detection and management of delirium in COVID-19.…”
Section: Discussionsupporting
confidence: 90%
See 1 more Smart Citation
“…Among 77 COVID-19 patients undergoing acute inpatient rehabilitation, 80.5% of patients demonstrated cognitive impairment, the majority of whom had mild deficits. This number is consistent with studies using neuropsychological assessments to evaluate cognition in hospitalized COVID-19 patients 5-6 and expands on these findings with a larger sample than previous studies. Consistent with the literature, delirium during acute hospitalization is associated with greater cognitive impairment at admission 10 , emphasizing the importance of early detection and management of delirium in COVID-19.…”
Section: Discussionsupporting
confidence: 90%
“…There is still limited knowledge on how cognitive deficits evolve and impact functional outcome. One study found 80% of COVID-19 patients on a rehabilitation unit had cognitive deficits, with continued impairment in over half of the patients at 1 month follow-up 6 ; however, the relationship to functional gain was not evaluated. This study aims to determine the magnitude and change in cognitive impairment, correlates of cognitive impairment, and the relation between cognition and function, in a relatively large sample of COVID-19 patients admitted to inpatient rehabilitation.…”
Section: Introductionmentioning
confidence: 99%
“…In December 2019, a new disease, the coronavirus disease 2019 (COVID- 19), emerged in China and rapidly spread over the world, resulting in a global pandemic on March 11, 2020. Scientific literature suggests that COVID-19 is associated with adverse mental health consequences for general population, hospital staff, and patients, leading to dramatic relapses in the healthcare system worldwide (1,2).…”
Section: Introductionmentioning
confidence: 99%
“…По данным одного из последних метаанализов, в общей сложности выявлено 55 симптомов, сохраняющихся у лиц после перенесенной острой коронавирусной инфекции. Пятью наиболее частыми проявлениями были утомляемость (58%, 95% ДИ: 42-73), головная боль (44%, 95% ДИ: 13-78), нарушение внимания (27%, 95% ДИ: [19][20][21][22][23][24][25][26][27][28][29][30][31][32][33][34][35][36], выпадение волос (25%, 95% ДИ: 17-34) и одышка (24%, 95% ДИ: 14-36) [12].…”
Section: распространенность когнитивных нарушений у лиц перенесших Cunclassified
“…В одной из последних работ показано, что среди 87 пациентов (62 мужчины, средний возраст 67,23 ± 12,89 года) после COVID-19 у 80% имелся нейропсихологический дефицит по данным MoCA и MMSE, при этом когнитивные нарушения коррелировали с возрастом пациентов [18]. В другом исследовании у 46 из 57 пациентов (81%) выявлялись когнитивные нарушения, причем больше всего пострадали внимание и исполнительные функции [19].…”
Section: распространенность когнитивных нарушений у лиц перенесших Cunclassified