COVID-19 as a confounding factor in a child submitted to staged surgical palliation of hypoplastic left heart syndrome: One of the first reports of SARS-CoV-2 infection in patients with congenital heart disease

Abstract

Graphical abstract

Impact of COVID-19 on patients with congenital heart disease

“…We identified 19 papers of which 12 were guidelines, commentary, or opinion and 7 included patient data ( Table 1). We included the 7 papers, [2][3][4][5][6][7][8] which contained actual patient data and this included a variety of case reports, case series, and retrospective reviews. We excluded the 12 papers 9-20 that did not include any patient data and were deemed guidelines, opinion pieces, or a commentary.…”

“…Specific CHD lesions reported in all other papers. [3][4][5][6][7][8] All other papers combined (n = 18)…”

COVID-19 and congenital heart disease: an insight of pathophysiology and associated risks

“…19,28 Out of the 12 studies we analysed, 5 included patients who were admitted to ICU. 12,15,19,20,22 Besides those previously mentioned, 19,22 Simpson et al reported 71% (n = 4) of patients being admitted to ICU. One of the patients recovered and was discharged and another recovered after surgical repair.…”

“…After the exclusion of duplicates, 12 articles were selected for inclusion into the analysis (Fig 1). [11][12][13][14][15][16][17][18][19][20][21][22] These comprised a total of 143 patients, of which 99 had CHDs. The key information from each article is summarised in Table 2.…”

“…Despite a complete AV block 5 days post-op and experiencing other complications, the patient fully recovered and was discharged on 24 days post-op. 12 Krishnan et al reported 67% (n = 2) of patients were admitted to ICU with 1 patient recovering on baseline medications and CPAP and 1 who recovered after receiving a tracheostomy collar. 15 Table 1.…”