Coverage percentage and raman measurement of cross-tile and scaffold cross-tile based DNA nanostructures

Gnapareddy, Bramaramba; Ahn, Sang Jung; Dugasani, Sreekantha Reddy; Kim, Jang Ah; Amin, Rashid; Mitta, Sekhar Babu; Vellampatti, Srivithya; Kim, Byeong‐Hoon; Kulkarni, Atul; Kim, Taesung; Yun, Kyusik; LaBean, Thomas H.; Park, Sungha

doi:10.1016/j.colsurfb.2015.08.013

Cited by 6 publications

(2 citation statements)

References 34 publications

(29 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…After the discovery of double-helical structures and evaluation of their intrinsic functions and properties, DNA molecules have attracted tremendous attention due to the programmability of the DNA base sequences that enables the design of various DNA nanostructures and applicability of DNA molecules to embed functionalized nanomaterials [1][2][3][4][5][6][7][8]. The additional advantages of using DNA in constructing nanostructures and thin films with dimensional precision and fabrication of efficient devices or sensors with functional enhancement are due to the exceptional features of DNA molecules, i.e.…”

Section: Introductionmentioning

confidence: 99%

Topological, chemical and electro-optical characteristics of riboflavin-doped artificial and natural DNA thin films

Gnapareddy¹,

Dugasani²,

Son³

et al. 2018

R. Soc. open sci.

Self Cite

View full text Add to dashboard Cite

DNA is considered as a useful building bio-material, and it serves as an efficient template to align functionalized nanomaterials. Riboflavin (RF)-doped synthetic double-crossover DNA (DX-DNA) lattices and natural salmon DNA (SDNA) thin films were constructed using substrate-assisted growth and drop-casting methods, respectively, and their topological, chemical and electro-optical characteristics were evaluated. The critical doping concentrations of RF ([RF]C, approx. 5 mM) at given concentrations of DX-DNA and SDNA were obtained by observing the phase transition (from crystalline to amorphous structures) of DX-DNA and precipitation of SDNA in solution above [RF]C. [RF]C are verified by analysing the atomic force microscopy images for DX-DNA and current, absorbance and photoluminescence (PL) for SDNA. We study the physical characteristics of RF-embedded SDNA thin films, using the Fourier transform infrared spectrum to understand the interaction between the RF and DNA molecules, current to evaluate the conductance, absorption to understand the RF binding to the DNA and PL to analyse the energy transfer between the RF and DNA. The current and UV absorption band of SDNA thin films decrease up to [RF]C followed by an increase above [RF]C. By contrast, the PL intensity illustrates the reverse trend, as compared to the current and UV absorption behaviour as a function of the varying [RF]. Owing to the intense PL characteristic of RF, the DNA lattices and thin films with RF might offer immense potential to develop efficient bio-sensors and useful bio-photonic devices.

show abstract

Section: Introductionmentioning

confidence: 99%

Topological, chemical and electro-optical characteristics of riboflavin-doped artificial and natural DNA thin films

Gnapareddy¹,

Dugasani²,

Son³

et al. 2018

R. Soc. open sci.

Self Cite

View full text Add to dashboard Cite

show abstract

“…Additionally; these DNA–organic hybrids are endowed with better base pairing fidelity, stability, DNA economy and others [ 41 – 42 ]. Supramolecular structures having a confined space can accommodate small molecules that are suitable for catalysis and other applications [ 43 – 44 ].These small molecules also provide the template for the construction of self-assembled supramolecular structures that undergo several self-correction steps in the due course of the construction of their complex structures [ 45 ]. These structures may be nanopores, nanofibers, nanotubes and polymeric networks [ 46 – 47 ].…”

Section: Introductionmentioning

confidence: 99%

Hierarchical coassembly of DNA–triptycene hybrid molecular building blocks and zinc protoporphyrin IX

Kumari¹,

Singh²,

Mohan³

et al. 2016

Beilstein J. Nanotechnol.

View full text Add to dashboard Cite

SummaryHerein, we describe the successful construction of composite DNA nanostructures by the self-assembly of complementary symmetrical 2,6,14-triptycenetripropiolic acid (TPA)–DNA building blocks and zinc protoporphyrin IX (Zn PpIX). DNA–organic molecule scaffolds for the composite DNA nanostructure were constructed through covalent conjugation of TPA with 5′-C12-amine-terminated modified single strand DNA (ssDNA) and its complementary strand. The repeated covalent conjugation of TPA with DNA was confirmed by using denaturing polyacrylamide gel electrophoresis (PAGE), reverse-phase high-performance liquid chromatography (RP-HPLC) and matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF). The biologically relevant photosensitizer Zn PpIX was used to direct the hybridization-mediated self-assembly of DNA–TPA molecular building blocks as well as a model guest molecule within the DNA–TPA supramolecular self-assembly. The formation of fiber-like composite DNA nanostructures was observed. Native PAGE, circular dichroism (CD) and atomic force microscopy (AFM) have been utilized for analyzing the formation of DNA nanofibers after the coassembly. Computational methods were applied to discern the theoretical dimension of the DNA–TPA molecular building block of the nanofibers. A notable change in photocatalytic efficiency of Zn PpIX was observed when it was inside the TPA–DNA scaffold. The significant increase in ROS generation by Zn PpIX when trapped in this biocompatible DNA–TPA hybrid nanofiber may be an effective tool to explore photodynamic therapy (PDT) applications as well as photocatalytic reactions.

show abstract

Sequence-specific fluorometric recognition of HIV-1 ds-DNA with zwitterionic zinc(II)-carboxylate polymers

Sun

Zhao

Xie

et al. 2017

Journal of Inorganic Biochemistry

View full text Add to dashboard Cite

Coverage percentage and raman measurement of cross-tile and scaffold cross-tile based DNA nanostructures

Cited by 6 publications

References 34 publications

Topological, chemical and electro-optical characteristics of riboflavin-doped artificial and natural DNA thin films

Topological, chemical and electro-optical characteristics of riboflavin-doped artificial and natural DNA thin films

Hierarchical coassembly of DNA–triptycene hybrid molecular building blocks and zinc protoporphyrin IX

Sequence-specific fluorometric recognition of HIV-1 ds-DNA with zwitterionic zinc(II)-carboxylate polymers

Contact Info

Product

Resources

About