Cost Effectiveness of Becaplermin in the Treatment of Diabetic Foot Ulcers in Four European Countries

Ghatnekar, Ola; Persson, Ulf; Willis, Michael; Ödegaard, Knut

doi:10.2165/00019053-200119070-00005

Cited by 51 publications

(33 citation statements)

References 10 publications

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“…39,40,42,52,53 Becaplermin as an adjunct to GWC has yielded favorable cost-effectiveness ratios in Canada, 39 France, 40 Sweden, 40,52 Switzerland, 40 the United Kingdom, 40 and the United States. 42,53,54 Studies inside and outside the United States have found that treatment with becaplermin has resulted in additional ulcer-free days and weeks and reduced long-term expenses, including office visits, dressings, recurrence rates, and amputation.…”

Section: Discussionmentioning

confidence: 99%

“…Costeffectiveness studies on the direct cost of care for DFU therapy included healing as the only primary outcome and did not include other potential surrogate endpoints, such as cost per cm 2 of WSA reduction. 39,40 Previous work by Margolis et al 41 found that percentage change in WSA can be used as a surrogate marker for complete wound healing. Access to health economic data will enable physicians and health-care decision makers in the United States to make better informed choices about treating DFUs.…”

Section: Platelet-derived Growth Factors and Wound Healingmentioning

confidence: 98%

See 1 more Smart Citation

Cost-Effectiveness of Becaplermin Gel on Diabetic Foot Ulcer Healing

Waycaster

Gilligan

Motley

2016

Journal of the American Podiatric Medical Association

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Section: Discussionmentioning

confidence: 99%

Section: Platelet-derived Growth Factors and Wound Healingmentioning

confidence: 98%

Cost-Effectiveness of Becaplermin Gel on Diabetic Foot Ulcer Healing

Waycaster

Gilligan

Motley

2016

Journal of the American Podiatric Medical Association

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“…In common with the industry submission, the results of Ghatnekar et al (2001) 247 are used for the costs of complications associated with uninfected ulcers, infected ulcers and gangrene, which, in 2006 prices, equate to event costs of £1643, £1684 and £2700, respectively. Again, these are slightly higher than those of the industry submission, probably due to different inflation rates having been assumed.…”

Section: Costs Of Complicationsmentioning

confidence: 99%

Clinical effectiveness and cost-effectiveness of continuous subcutaneous insulin infusion for diabetes: systematic review and economic evaluation

Cummins

Royle²,

Snaith³

et al. 2010

Health Technol Assess

184

155

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“…102 Baseline probabilities were taken from a prospective study of 183 patients and becaplermin efficacy was based on 20-week healing rates in a meta-analysis of clinical trials with 449 patients. Country-specific economic data, established through expert opinion, were integrated into the model to generate cost-effectiveness ratios.…”

Section: Empirical Analyses Of Geographical Variability In Modelling mentioning

confidence: 99%

Generalisability in economic evaluation studies in healthcare: a review and case studies

Sculpher

Fs²,

Manca³

et al. 2004

Health Technol Assess

318

297

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Cost Effectiveness of Becaplermin in the Treatment of Diabetic Foot Ulcers in Four European Countries

Cited by 51 publications

References 10 publications

Cost-Effectiveness of Becaplermin Gel on Diabetic Foot Ulcer Healing

Cost-Effectiveness of Becaplermin Gel on Diabetic Foot Ulcer Healing

Clinical effectiveness and cost-effectiveness of continuous subcutaneous insulin infusion for diabetes: systematic review and economic evaluation

Generalisability in economic evaluation studies in healthcare: a review and case studies

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