Cost-effectiveness analysis of pertussis vaccination during pregnancy in Japan

Hoshi, Shu-ling; Seposo, Xerxes; Okubo, Ichiro; Kondo, Masahide

doi:10.1016/j.vaccine.2018.07.026

Cited by 14 publications

(13 citation statements)

References 31 publications

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“…Thirty-six studies addressed the technical value as a key element. The majority (eight studies; 22.22%) of the studies concerned influenza vaccines ( 35 , 38 , 48 – 52 , 58 ) and HPV (eight studies; 22.22%) ( 27 , 33 , 40 – 42 , 46 , 55 , 61 ), five pneumococcal vaccines (13.9%) ( 34 , 36 , 44 , 45 , 62 ), three rotavirus (8.3%) ( 39 , 47 , 59 ), while six (16.7%) multiple vaccines ( 31 , 32 , 37 , 43 , 56 , 60 ). Eventually, six (16.67%) did not address any specific vaccines in particular ( 25 , 26 , 29 , 53 , 54 , 57 ).…”

Section: Resultsmentioning

confidence: 99%

“…With respect to specific dimensions considered within the pillar, a total of 19 (52.8%) papers focused on the cost-effectiveness, including also the cost-utility ( 25 , 27 , 32 , 34 , 35 , 37 , 38 , 40 , 43 , 44 , 46 – 48 , 50 , 53 , 56 , 59 – 61 ). Six studies (16.7%) addressed the cost of illness ( 48 – 50 , 54 , 58 , 62 ), two (5.6%) the cost-benefit ( 33 , 55 ), and one (2.8%) the budget impact ( 45 ).…”

Section: Resultsmentioning

confidence: 99%

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The Value(s) of Vaccination: Building the Scientific Evidence According to a Value-Based Healthcare Approach

Calabrò

Carini

Tognetto

et al. 2022

Front. Public Health

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ObjectivesTo provide a new value-based immunization approach collating the available scientific evidence on the topic.MethodsFour value pillars (personal, allocative, technical, and societal) applied to vaccination field were investigated. A systematic literature review was performed querying three database from December 24th, 2010 to May 27th, 2020. It included studies on vaccine-preventable diseases (VPDs) that mentioned the term value in any part and which were conducted in advanced economies. An in-depth analysis was performed on studies addressing value as key element.ResultsOverall, 107 studies were considered. Approximately half of the studies addressed value as a key element but in most of cases (83.3%) only a single pillar was assessed. Furthermore, the majority of papers addressed the technical value by looking only at classical methods for economic assessment of vaccinations whereas very few dealt with societal and allocative pillars.ConclusionsEstimating the vaccinations value is very complex, even though their usefulness is certain. The assessment of the whole value of vaccines and vaccinations is still limited to some domains and should encompass the wider impact on economic growth and societies.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

The Value(s) of Vaccination: Building the Scientific Evidence According to a Value-Based Healthcare Approach

Calabrò

Carini

Tognetto

et al. 2022

Front. Public Health

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“…Based on these studies, we assume that Tdap vaccination coverage during pregnancy is still poor in Italy. Taking into account the costs of hospitalisation and the fact that severe pertussis cases mostly occur in children too young to be eligible for vaccination, immunisation in pregnancy remains a mainstay of pertussis prevention and should be urgently implemented and promoted, given its efficacy, safety and cost-effectiveness and that it had a higher impact than a cocooning strategy or immunisation before pregnancy [27,32]. Nevertheless, a pertussis vaccination programme in pregnancy may have a limited impact on preventing pertussis among preterm infant (over-represented among infants hospitalised with pertussis), because the opportunity for maternal vaccination is smaller in this particular group, as previously demonstrated in a study conducted in the UK.…”

Section: Although Pertussis Vaccination Coverage Acrossmentioning

confidence: 99%

The impact of pertussis in infants: insights from a hospital-based enhanced surveillance system, Lazio region, Italy, 2016 to 2019

et al. 2021

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Background Routine surveillance systems for pertussis often suffer from under-recognition and under-reporting. Aim Our aim was to describe the epidemiology and the clinical features of pertussis in children younger than 1 year in an Italian region, detected through an enhanced hospital surveillance system. Methods From 2016 to 2019, we monitored the incidence and the clinical characteristics of hospitalised pertussis cases younger than 1 year in two paediatric hospitals involved in the PERTINENT project. Results We detected 141 pertussis cases, corresponding to an estimated incidence of 105.8 per 100.000 in 2016, 91.7 per 100.000 in 2017, 64.5 per 100.000 in 2018 and 40.9 per 100.000 in 2019, based on the hospitals’ catchment area, roughly corresponding to the Lazio region. A total of 101 cases (77.1%) had a household member with cough or other respiratory symptoms. The most frequent combination of symptoms was paroxysmal cough with apnoea in the absence of fever. Almost 40% had been prescribed an antibiotic treatment before hospitalisation, and the median time from symptom onset to contact with the hospital was 8 days. Thirty-one (22.0%) had complications. Conclusion An enhanced surveillance system showed a high incidence of pertussis among infants in the Lazio region, where the impact of this disease may still be underestimated. Increasing the coverage of pertussis immunisation among pregnant women and improving the capacity for early detection in primary care may contribute to reducing the impact of pertussis among infants.

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“…Beban biaya selanjutnya dilakukan discounting dengan faktor discounting sebesar 3% setiap tahunnya. 6 Perspektif pada penelitian ini adalah payer perspective, yaitu BPJS Kesehatan. Beban biaya yang dimaksud merupakan besaran biaya langsung medik yang harus ditanggung oleh BPJS Kesehatan.…”

Section: Pendahuluanunclassified

Analisis Efektivitas Biaya Penggunaan Kontrasepsi di Indonesia Tahun 2014–2017

Khoiriyah

Zakiyah

Suwantika

2019

ijcp

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Keluarga berencana menjadi salah satu program kesehatan dan kependudukan di Indonesia yang pembiayaannya dijamin oleh sistem Jaminan Kesehatan Nasional (JKN). Tujuan penelitian ini adalah mengetahui analisis efektivitas biaya penggunaan kontrasepsi hormonal dan nonhormonal di Indonesia pada tahun 2014-2017. Penelitian ini merupakan penelitian kuantitatif menggunakan data sekunder dengan pengambilan data dilakukan secara retrospektif, dan dilaksanakan di Fakultas Farmasi Universitas Padjadjaran pada bulan Oktober 2018 hingga Januari 2019. Metode yang digunakan pada penelitian ini adalah analisis efektivitas biaya dengan menghitung Incremental Cost-effectiveness Ratio (ICER). Perspektif biaya yang digunakan adalah payer perspective (BPJS Kesehatan). Hasil penelitian menunjukkan bahwa beban biaya penggunaan kontrasepsi hormonal pada tahun 2014-2017 di Indonesia memiliki nilai yang lebih rendah dibandingkan beban biaya penggunaan kontrasepsi nonhormonal. Dari segi efektivitas, kontrasepsi nonhormonal memiliki efektivitas yang lebih rendah dibandingkan efektivitas hormonal. Simpulan penelitian ini adalah kontrasepsi hormonal lebih cost-effective dengan nilai ICER kontrasepsi hormonal sebesar Rp64.471/ 1% kehamilan yang dapat dicegah sedangkan nilai ICER kontrasepsi nonhormonal sebesar Rp341.003/1% kehamilan yang dapat dicegah. Analisis sensitivitas menunjukkan bahwa efektivitas metode kontrasepsi menjadi faktor paling berpengaruh terhadap nilai ICER.

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Cost-effectiveness analysis of pertussis vaccination during pregnancy in Japan

Cited by 14 publications

References 31 publications

The Value(s) of Vaccination: Building the Scientific Evidence According to a Value-Based Healthcare Approach

The Value(s) of Vaccination: Building the Scientific Evidence According to a Value-Based Healthcare Approach

The impact of pertussis in infants: insights from a hospital-based enhanced surveillance system, Lazio region, Italy, 2016 to 2019

Analisis Efektivitas Biaya Penggunaan Kontrasepsi di Indonesia Tahun 2014–2017

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