Cost-effective Management of Sore Throat

Cost and effectiveness analysis of the diagnostic and therapeutic approaches of group A Streptococcus pharyngitis management in Iran

“…[202627] In addition, the probability of the streptococcal origin of the sore throat in Iranian studies ranged between 7.5 and 31%,[72829] whereas the rate reported for other countries ranged between 20 and 36%. [101119202630] Moreover, the effect of penicillin in reducing the symptoms of pharyngitis was 70–89%,[1419203132] i.e. it decreases symptoms by 8–10 times.…”

“…In addition, according to the analysis of the pharyngitis group a streptococcus (PGAS) variable, the RTA option followed by culture is still the most preferred option to manage the disease. Meanwhile, different authors have reported different results; for instance, studies such as Tsevat and Kotagal[31] have claimed that the culture was the best option, whereas Ehrlich et al [20] proposed RTA as the best option.…”

Does This Patient Have Strep Throat?

“…Some would argue that a throat culture is always necessary and that treatment should be delayed until culture results become available. 41 However, this approach ignores the accuracy of newer rapid antigen tests, particularly when used in tandem with an accurate assessment of the pretest probability using a clinical score. A recent study of 30 000 episodes of sore throat found that changing from a policy encouraging throat culture to one encouraging the use of a rapid antigen test only, with a corresponding decrease of 65% to 13% in the percentage of patients with sore throat receving a culture, did not change the number of suppurative complications.…”

Pharmacoeconomic evaluation of cefaclor in the pharyngo-tonsillitis and acute otitis in children

“…La costo/efficacia di cefaclor versus altri antibiotici nel trattamento delle FT e delle OMA in età pediatrica non risulta essere stata ancora ben documentata, soprattutto in Italia e in relazione alle reali condizioni d'impiego [73,74]. I costi sanitari e non sanitari delle FT e delle OMA e delle diverse strategie di gestione dei pazienti pediatrici affetti da queste infezioni sono stati analizzati in diversi studi, nessuno dei quali però condotto in Italia [6][7][8][9][10][11][12][13][75][76][77][78][79][80][81][82][83][84][85][86][87][88][89][90][91][92][93][94].…”