Cortisone Acetate Administered Orally in Dermatologic Therapy

Introduction:Topical corticosteroids (TCS) have been widely used in various dermatological diseases. However, because of inadvertent use, TCS misuse has become a common problem faced by dermatologists in various parts of the world. Prolonged use over the face can cause various side effects such as steroid rosacea, acneiform eruptions, and hypertrichosis.Aim:To study the effects of TCS misuse and analyze various factors promoting its use on face.Materials and Methods:A total of 100 patients presenting with various facial dermatoses following the misuse of TCS on the face were studied. Detailed history was noted and the various side effects were recorded.Results:Majority of the patients (70%) were females with maximum number of patients belonging to the age group of 11–20 years. Eighty-five percent of the patients were applying TCS for medical conditions, with acne being the most common indication, and the rest were applying as a general face cream. Pruritus and acneiform eruptions were the most common side effects observed and the other reported were erythema, photosensitivity, steroid dependent face, and telangiectasia.Conclusion:TCS misuse especially over the face can lead to a multitude of side effects. It is high time to create awareness among the patients as well as doctors regarding the proper usage of this wonder drug.

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“…[ 3 ] TCS also have potent antipruritic, atrophogenic, melanopenic, immunosuppressive, and ex-hormone like effect on the skin. [ 4 ]…”

Section: Introductionmentioning

confidence: 99%

Misuse of topical corticosteroids over face: A clinical study

Manchanda

Mohanty

Rohatgi

2017

Indian Dermatol Online J

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“…Topical corticosteroids (TCS) are of great value in treating a wide spectrum of dermatological diseases and since the time of its introduction in 1951, a new therapeutic era in dermatology has been emerged [1]. …”

Section: Introductionmentioning

confidence: 99%

Steroid Dermatitis Resembling Rosacea: A Clinical Evaluation of 75 Patients

Hameed

2013

ISRN Dermatology

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Background. The use of topical steroids on the skin of the face should be carefully evaluated by the dermatologist; however, its misuse still occurs producing dermatological problem resembling rosacea. Objectives. To report the different clinical manifestations of steroid dermatitis resembling rosacea and to discover causes behind abusing topical steroids on the face. Methods. In this prospective observational study, 75 patients with steroid dermatitis resembling rosacea who had history of topical steroid use on their faces for at least 1–3 months were evaluated at the Department of Dermatology, Baghdad Teaching Hospital, between August 2010 and December 2012. Results. The majority of patients were young women who used a combinations of potent and very potent topical steroid for average period of 0.25–10 years. Facial redness and hotness, telangiectasia, and rebound phenomenon with papulopustular eruption were the main clinical presentations. The most common causes of using topical steroid on the face were pigmentary problems and acne through recommendations from nonmedical personnel. Conclusion. Topical steroid should not be used on the face unless it is under strict dermatological supervision.

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“…Philip Hench, a clever rheumatologist at the Mayo Clinic, following a "hunch" consulted Kendall about the use of Compound E in the treatment of arthritis. This may have been one of the first controlled clinical trials in the USA: (Hench et al 1950) efficacy in arthritis was confirmed, a) oral cortisone for dermatologic diseases (Sulzberger et al 1951). Despite their many problems oral corticosteroids, mostly prednisone or prednisolone, are being used widely as anti-inflammatory oral agents, but not in psoriasis or atopic dermatitis, two important and still untreatable common diseases in dermatology.…”

Section: Immunomodulatorylanti-proliferative Agentsmentioning

confidence: 93%

Dermatology 1945–95: The Golden Age of Treatment

Fitzpatrick

1996

The Journal of Dermatology

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Cortisone Acetate Administered Orally in Dermatologic Therapy

Cited by 39 publications

References 1 publication

Misuse of topical corticosteroids over face: A clinical study

Misuse of topical corticosteroids over face: A clinical study

Steroid Dermatitis Resembling Rosacea: A Clinical Evaluation of 75 Patients

Dermatology 1945–95: The Golden Age of Treatment

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