Corticosteróide tópico oclusivo no tratamento de manifestações gengivais de doenças vesicobolhosas auto-imunes

Motta, Ana Carolina Fragoso; Grisi, Márcio Fernando de Moraes; Souza, Cacilda da Silva; Roselino, Ana Maria Ferreira; Migliari, Dante Antônio

doi:10.1590/s0365-05962006000300011

Cited by 2 publications

(3 citation statements)

References 10 publications

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“…As for BMMP and its clinical signs, some studies have shown that desquamative gingivitis can be present in up to 95% of cases [5,11,12]. Erosive flat lichen and, less frequently, pemphigus vulgaris may also cause desquamative gingivitis [5].…”

Section: Discussionmentioning

confidence: 99%

“…The changes caused by BMMP in the oral epithelium affect periodontal health, facilitating the accumulation of dental biofilm and changing periodontal parameters. Bleeding, probing depth, and the clinical insertion level may make diagnosing the condition challenging due to the overlapping clinical signs of different autoimmune diseases and periodontal changes [3,11,12].…”

Section: Discussionmentioning

confidence: 99%

“…In more severe cases, the elimination of gingival irritative factors such as dental biofilm and calculus should also be treated with the association of drug therapy [5]. As it is a dermatosis, multidisciplinary follow-up with a dental surgeon and dermatologist is essential [12].…”

Section: Discussionmentioning

confidence: 99%

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Benign Mucosal Membrane Pemphigoid as a Differential Diagnosis of Necrotizing Periodontal Disease

Storrer

Junior

Teixeira³

et al. 2020

Case Reports in Dentistry

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Desquamative gingivitis is an oral sign of systemic changes that may be symptomatic or asymptomatic. It is generally related to immunological changes. This report is aimed at describing the case of a 51-year-old female patient, who presented with clinical desquamative gingivitis and was initially diagnosed and treated as necrotizing periodontal disease, but no improvement. The cause was hypothesized to be an autoimmune disease. Drug therapy was initiated as a combination of prednisone and topical clobetasol propionate 0.5% cream twice a day. After this treatment, there was an improvement in pain and the blistering of the gingiva. However, the gingiva remained erythematous. A biopsy led to the diagnosis of benign mucous membrane pemphigoid (BMMP). The BMMP case reported in this article has been successfully treated with systemic and topical immunosuppressive therapy. The efficacy of systemic corticosteroids with dapsone and multidisciplinary follow-up has been highlighted and can lead to the stabilization and adequate control of the disease.

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