Correlative Angiographic and Pathologic Findings in the Diagnosis of Ulcerated Plaques in the Carotid Artery

Can Arteriography Serve a Diagnostic Purpose in Plaque Type VI by AHA Identification in Patients with Internal Carotid Artery Stenosis ?

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Can Arteriography Serve a Diagnostic Purpose in Plaque Type VI by AHA Identification in Patients with Internal Carotid Artery Stenosis ?

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Angiographic detection of carotid plaque ulceration. Comparison with surgical observations in a multicenter study. North American Symptomatic Carotid Endarterectomy Trial.

“…3 " 8 The sensitivity of detecting plaque ulceration ranged from 53% to 86% as reported in these studies. Further comparisons among these studies are complicated by the comparative standard that was used to verify the presence of plaque ulceration and by the variable definitions that were used for the angiographic diagnosis of ulceration.…”

“…Some prefer the reports of microscopic examinations, 8 but the detection of the smallest discontinuity in the endothelium makes this method an impractical standard to be followed.…”

Reproducibility of Histological Assessment of Carotid Plaque: Implications for Studies of Carotid Imaging

“…However, the results of these studies have been very variable, even between studies using the same imaging criteria, such as the Gray-Weale scale of ultrasound echogenicity [26, 28, 29, 30]or angiographic plaque surface morphology [13, 14, 15, 16, 20, 22], and correlation has sometimes been poor. It is uncertain to what extent this might have been due to variability in the quality of the histological assessment.…”

Can Arteriography Serve a Diagnostic Purpose in Plaque Type VI by AHA Identification in Patients with Internal Carotid Artery Stenosis ?

“……”

Angiographic detection of carotid plaque ulceration. Comparison with surgical observations in a multicenter study. North American Symptomatic Carotid Endarterectomy Trial.

“…3 " 8 The sensitivity of detecting plaque ulceration ranged from 53% to 86% as reported in these studies. Further comparisons among these studies are complicated by the comparative standard that was used to verify the presence of plaque ulceration and by the variable definitions that were used for the angiographic diagnosis of ulceration.…”

“…Some prefer the reports of microscopic examinations, 8 but the detection of the smallest discontinuity in the endothelium makes this method an impractical standard to be followed.…”

Reproducibility of Histological Assessment of Carotid Plaque: Implications for Studies of Carotid Imaging

“…However, the results of these studies have been very variable, even between studies using the same imaging criteria, such as the Gray-Weale scale of ultrasound echogenicity [26, 28, 29, 30]or angiographic plaque surface morphology [13, 14, 15, 16, 20, 22], and correlation has sometimes been poor. It is uncertain to what extent this might have been due to variability in the quality of the histological assessment.…”

Can Arteriography Serve a Diagnostic Purpose in Plaque Type VI by AHA Identification in Patients with Internal Carotid Artery Stenosis ?

“……”

Angiographic detection of carotid plaque ulceration. Comparison with surgical observations in a multicenter study. North American Symptomatic Carotid Endarterectomy Trial.

“…3 " 8 The sensitivity of detecting plaque ulceration ranged from 53% to 86% as reported in these studies. Further comparisons among these studies are complicated by the comparative standard that was used to verify the presence of plaque ulceration and by the variable definitions that were used for the angiographic diagnosis of ulceration.…”

“…Some prefer the reports of microscopic examinations, 8 but the detection of the smallest discontinuity in the endothelium makes this method an impractical standard to be followed.…”

Reproducibility of Histological Assessment of Carotid Plaque: Implications for Studies of Carotid Imaging

“…However, the results of these studies have been very variable, even between studies using the same imaging criteria, such as the Gray-Weale scale of ultrasound echogenicity [26, 28, 29, 30]or angiographic plaque surface morphology [13, 14, 15, 16, 20, 22], and correlation has sometimes been poor. It is uncertain to what extent this might have been due to variability in the quality of the histological assessment.…”