Correlation of Initial Thiothixene Serum Levels and Clinical Response

Yesavage, Jerome A.

doi:10.1001/archpsyc.1983.01790030071009

Arch Gen Psychiatry

1983

DOI: 10.1001/archpsyc.1983.01790030071009

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Correlation of Initial Thiothixene Serum Levels and Clinical Response

Jerome A. Yesavage¹

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Cited by 14 publications

(3 citation statements)

References 15 publications

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2

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“…A positive correlation ( r = 0.51) was found between peak drug concentration and BPRS score. A similar correlation ( r = 0.50) was found when the number of patients was increased to 48 (Yesavage et al 1983).…”

Section: Fixed-dose Plasma Level Studies With Neuroleptics

supporting

confidence: 75%

“…It is unknown whether this patient would have improved at a lower plasma level, but the authors suggested a therapeutic range of 2-15.0 ng/ml. Yesavage et al (1982Yesavage et al ( , 1983) ) measured plasma THX 2.5 hours after a 30-mg oral dose in 28 schizophrenic patients who had been treated with 80 mg of THX for 7 to 10 days. A positive correlation (r = 0.51) was found between peak drug concentration and BPRS score.…”

Section: 06

mentioning

confidence: 99%

“…Yesavage et al (1982, 1983) measured plasma THX 2.5 hours after a 30-mg oral dose in 28 schizophrenic patients who had been treated with 80 mg of THX for 7 to 10 days. A positive correlation ( r = 0.51) was found between peak drug concentration and BPRS score.…”

Section: Fixed-dose Plasma Level Studies With Neuroleptics

mentioning

confidence: 99%

See 2 more Smart Citations

Neuroleptic Plasma Levels

Putten

¹

,

Marder

²

,

Wirshing

³

et al. 1991

Schizophrenia Bulletin

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Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.

“…A positive correlation ( r = 0.51) was found between peak drug concentration and BPRS score. A similar correlation ( r = 0.50) was found when the number of patients was increased to 48 (Yesavage et al 1983).…”

Section: Fixed-dose Plasma Level Studies With Neuroleptics

supporting

confidence: 75%

“…It is unknown whether this patient would have improved at a lower plasma level, but the authors suggested a therapeutic range of 2-15.0 ng/ml. Yesavage et al (1982Yesavage et al ( , 1983) ) measured plasma THX 2.5 hours after a 30-mg oral dose in 28 schizophrenic patients who had been treated with 80 mg of THX for 7 to 10 days. A positive correlation (r = 0.51) was found between peak drug concentration and BPRS score.…”

Section: 06

mentioning

confidence: 99%

“…Yesavage et al (1982, 1983) measured plasma THX 2.5 hours after a 30-mg oral dose in 28 schizophrenic patients who had been treated with 80 mg of THX for 7 to 10 days. A positive correlation ( r = 0.51) was found between peak drug concentration and BPRS score.…”

Section: Fixed-dose Plasma Level Studies With Neuroleptics

mentioning

confidence: 99%

See 1 more Smart Citation

Neuroleptic Plasma Levels

Putten

¹

,

Marder

²

,

Wirshing

³

et al. 1991

Schizophrenia Bulletin

Get access via publisher Add to collection Cite

Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.

Therapeutic Drug Monitoring: Principles and Practice

Preskorn

¹

,

Burke

²

,

Fast

³

1993

Psychiatric Clinics of North America

Get access via publisher Add to collection Cite

Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.

A Critical Assessment of Antipsychotic Drug Monitoring

Waraska

¹

,

Nagle

²

1987

Clinics in Laboratory Medicine

Get access via publisher Add to collection Cite

Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.

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