Correlation of anti-wrinkling and free radical antioxidant activities of Areca nut with phenolic and flavonoid contents

Byun, Na-Young; Heo, Mi-Ra; Yim, Soon‐Ho

doi:10.1590/fst.35520

Cited by 18 publications

(10 citation statements)

References 21 publications

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“…The DPPH radical scavenging activities of yuzu varieties ranged from 24.28% to 26.72%, with the lowest value of 24.28% at Namhae variety (Table 3). There is a high correlation between the total phenol content and free radical scavenging activity (Byun et al, 2021). This is consistent with the research results stating that the DPPH radical scavenging activity is an indicator (1) By using Duncan's multiple range test, the mean with the same letter in each column is not significantly different ( p < 0.05).…”

Section: Dpph and Abts Radical Scavenging Activitysupporting

confidence: 90%

Physiochemical properties and neuroprotective function of Korean major yuzu varieties

et al. 2022

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Three major yuzu varieties, Native, Namhae, and Tadanishiki in Korea were investigated on physiochemical properties and functional characterizations with respect to neuroprotective function (SH-SY5Y cells) or anti-inflammatory (Raw 264.7 cells). Among the three cultivars tested, Namhae had significantly higher fruit weight and total dietary fibers, while Tadanishiki had higher values of both total flavonoid and antioxidant activity. As functional compounds, Tadanishiki contained a 133% of hesperidin and 164% of naringin, compared to those of Native or Namhae. In comparison to other yuzu, Tadanishiki showed the higher cell viability, lower AChE content, lower protein levels of Bcl-2 /Bax, Caspase 3, and PARP at scopolamine-treated SH-SY5Y nerve cell. Tadanishiki and Namhae were effective for anti-inflammation by decreasing of NO production in LPSinduced Raw 264.7 cells. These results indicate that Tadanishiki yuzu, could be useful for application as a possible natural functional additive with high hesperidin content and excellent neuroprotective and anti-inflammation effects.

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Section: Dpph and Abts Radical Scavenging Activitysupporting

confidence: 90%

Physiochemical properties and neuroprotective function of Korean major yuzu varieties

et al. 2022

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“…Considering several previous reports of potential elastase and tyrosinase inhibitory action of plant extracts [ 8 , 16 , 17 ], it was likely that the extracts possess a high antioxidant potential and tend to have strong elastase and tyrosinase inhibitory action. Thus to verify those relationships in this study, we further performed Pearson’s correlation analysis to investigate the relationship between the inhibitory activities of both enzymes and the level of antioxidant contents as well as antioxidant capacities among the extracts used.…”

Section: Resultsmentioning

confidence: 99%

Antioxidant and Anti-Skin Aging Potential of Selected Thai Plants: In Vitro Evaluation and In Silico Target Prediction

Chaikhong

Chumpolphant

Rangsinth

et al. 2022

Plants

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The skin is the largest organ that performs a variety of the body’s essential functions. Impairment of skin structure and functions during the aging process might severely impact our health and well-being. Extensive evidence suggests that reactive oxygen species play a fundamental role in skin aging through the activation of the related degradative enzymes. Here, the 16 Thai medicinal plant species were screened for their potential anti-skin aging properties. All extracts were investigated for total phenolic and flavonoid contents, antioxidant, anti-elastase, and anti-tyrosinase activities, as well as the binding ability of compounds with target enzymes by molecular docking. Among all the plants screened, the leaves of A. occidentale and G. zeylanicum exhibited strong antioxidants and inhibition against elastase and tyrosinase. Other potential plants include S. alata leaf and A. catechu fruit, with relatively high anti-elastase and anti-tyrosinase activities, respectively. These results are also consistent with docking studies of compounds derived from these plants. The inhibitory actions were found to be more highly positively correlated with phenolics than flavonoids. Taken together, our findings reveal some Thai plants, along with candidate compounds as natural sources of antioxidants and potent inhibitors of elastase and tyrosinase, could be developed as promising and effective agents for skin aging therapy.

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“…The inhibition activity of ABTS radicals were analyzed using a modi ed method previously described by Byun et al, (2021) with slight modi cation. The reagent was incubated for 24 hours at 37°C after being mixed with 7.4 mM ABTS and 2.45 mM potassium persulfate solution in a 1:1 (v/v) ratio.…”

Section: Determination Of Total Flavonoid Contentmentioning

confidence: 99%

Phytochemical analysis, antioxidants, α-glucosidase inhibitory activity, and Toxicity Evaluation of Orthosiphon stamineus leaf extract

Ahda

Jaswir

Khatib

et al. 2023

Preprint

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The potency of O. stamineus as a herbal candidate has been evaluated by previous studies. The goal of this study is to compare water and a 100% ethanolic extract of O. stamineus to see which one is more effective as an α-glucosidase inhibitor and antioxidant. However, these parameters are critical in the development of herbal medicines. Furthermore, the toxicity of this herb is assessed. According to this study, water extract of O. stamineus leaves has a better inhibition activity of α-glucosidase, ABTS, and DPPH, with IC50 values of approximately 43.623±0.039 µg/mL, 27.556±0.125 µg/mL, and 95.047±1.587 µg/mL, respectively. The major active compounds are fatty acid groups such as Ethyl myristate (Tr: 20.8 min); 6-(Stearoyloxy)octadecanoic acid (Tr: 20.75 min); Linoleic acid (Tr: 23.09 min); Oleic acid (Tr: 23.22 min); and phenolic groups including D-(-)-Quinic acid (Tr:1.3 min) and Caffeic acid (Tr: 5.2 min); and carboxylic acid groups and its derivate including 2-(Benzoyloxy)-3-hydroxysuccinic acid (Tr: 7.85 min) and Tuberonic acid (Tr: 9.67 min). Therefore, this study also found that the water extract of this herb is non-toxic to zebrafish embryos and has no effect on zebrafish larvae development at concentrations less than 500 g/mL.

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Correlation of anti-wrinkling and free radical antioxidant activities of Areca nut with phenolic and flavonoid contents

Cited by 18 publications

References 21 publications

Physiochemical properties and neuroprotective function of Korean major yuzu varieties

Physiochemical properties and neuroprotective function of Korean major yuzu varieties

Antioxidant and Anti-Skin Aging Potential of Selected Thai Plants: In Vitro Evaluation and In Silico Target Prediction

Phytochemical analysis, antioxidants, α-glucosidase inhibitory activity, and Toxicity Evaluation of Orthosiphon stamineus leaf extract

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