2004
DOI: 10.1590/s1678-91992004000300008
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Abstract: Seventy-nine HIV-1 infected patients were studied in three groups: Group G1 - 11 patients with no antiretroviral therapy; G2 - 40 patients undergoing antiretroviral therapy, 33 with only two nucleoside reverse transcriptase inhibitors (NRTI), and seven with two NRTI and one protease inhibitor (PI), all with viral load (VL) equal or higher than 80 copies of plasma RNA/ml; Group G3 - 28 patients, 23 on highly active antiretroviral therapy (HAART), 18 with two NRTI and one PI, and five with two NRTI and one non-n… Show more

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Cited by 4 publications
(52 citation statements)
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References 32 publications
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“…Another study was conducted by Meira et al, showed the positive correlation between IL-2 and IFN-which is the Th1 subset's de ner. In contrast to the study by Meira et al, in COVID-19 nasopharyngeal swab samples, we observed a strong positive correlation of IL-2 with IFN-γ, IL-4, IL-10, TNF-α, and TGF-β1 [30]. Another study indicated a positive correlation between IL-4 and TNF-α, but a negative correlation between IL-4 and IL-6 after ERCP (Endoscopic Retrograde Cholangio Pancreatography) [31].…”
Section: Discussioncontrasting
confidence: 99%
“…Another study was conducted by Meira et al, showed the positive correlation between IL-2 and IFN-which is the Th1 subset's de ner. In contrast to the study by Meira et al, in COVID-19 nasopharyngeal swab samples, we observed a strong positive correlation of IL-2 with IFN-γ, IL-4, IL-10, TNF-α, and TGF-β1 [30]. Another study indicated a positive correlation between IL-4 and TNF-α, but a negative correlation between IL-4 and IL-6 after ERCP (Endoscopic Retrograde Cholangio Pancreatography) [31].…”
Section: Discussioncontrasting
confidence: 99%
“…Also the pro-inflammatory mediator TNF-α seen to be elevated in the study was reported to be implicated in HIV pathogenesis through induction of virus transcription-activating factors [ 17 ]. Previous studies conducted by Meira et al [ 18 ] documented lower TNF-α, IL-4 and IL-10 serum level among HIV-1 mono-infected ART-experienced compared to their ART-naive counterparts. Similarly, elevated levels of TNF-α have been reported in mononuclear phagocytes during HIV, and which significantly decline during HAART [ 19 ].…”
Section: Discussionmentioning
confidence: 93%
“…The cytokines transducer signals and multiple protein kinase pathways have been involved in this process. The balance between proliferation and apoptosis to regulate the size and diversity of mature naive and memory Tcell pools in the peripheral circulation could also contribute (Meira et al, 2004;Silas et al, 2016).…”
Section: Discussionmentioning
confidence: 99%