Correlation between ApoE alleles and obesity markers in adults

Abstract

less information exist concerning the effect of the MD on the secondary prevention of CHD. Aim: The aim of this study is to investigate the effect of MD on the risk of cardiovascular event onset and cardiovascular mortality in patients who have suffered an Acute Coronary Syndrome (ACS). Materials and methods: A perspective, multicenter study of ten yearfollow-up (GREECS-Greek Study of ACS) was conducted (2004-2014). In the study 2.172 individuals (76% male) with ACS were enrolled from 6 hospitals in urban and rural Greek regions. In the information obtained anthropometric and socio-demographic characteristics, lifestyle habits, nutritional and psychological assessment and medical history were included. To assess the degree of adherence to the MD, the MedDietScore tool (range: 0-55) was used. The statistical analysis included: a) analysis of descriptive characteristics and b) development of multiple logarithmic regression models. Results: Greater adoption of the MD was associated with lower risk for fatal cardiovascular event (OR: 0,979, 95%CI: 0,960-0,998) after adjustment for age and sex. However, the statistical significance of the Mediterranean dietary pattern was attenuated (OR: 0,977, 95%CI: 0,953-1,002) when traditional cardiovascular risk factors were added to the model. The factor that seems to affect the relationship of the MD with cardiovascular mortality is physical activity. The level of adherence to the MD was not associated with the onset of a new cardiovascular event. Conclusions: The adoption of the MD reduces the risk of a fatal cardiovascular episode, without affecting the risk of next cardiovascular event in patients with ACS.