Coronavirus disease 2019 (COVID-19) vaccination in systemic lupus erythematosus and anti-neutrophil cytoplasmic antibody-associated vasculitis

Sim, Jackie Jia Lin; Lim, Cynthia Ciwei

doi:10.1007/s10067-021-05750-3

Cited by 1 publication

(3 citation statements)

References 11 publications

(9 reference statements)

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“…The following information was obtained using a standardized survey form: sociodemographic data such as age, gender, ethnicity, highest education attained, occupation personal gross monthly income (less than $4,000 vs. ≥$4,000), housing type (public vs. private), language spoken at home (English, Mandarin, Malay, Tamil, others) and frequency of visits to healthcare institutions such as clinic or hospital in the past 6 months. Health literacy was assessed using the HLS-EU-Q47 questionnaire, a 47-item survey with each item rated on a 4-point Likert scale for perceived level of difficulty in the competencies of accessing, understanding, evaluating, and applying healthcare-related information in the domains of healthcare, disease prevention, and health promotion [ 15 , 17 ]. It had good construct validity, item-scale convergent validity, internal consistency, and no floor or ceiling effect [ 17 ].…”

Section: Methodsmentioning

confidence: 99%

“…Health literacy was assessed using the HLS-EU-Q47 questionnaire, a 47-item survey with each item rated on a 4-point Likert scale for perceived level of difficulty in the competencies of accessing, understanding, evaluating, and applying healthcare-related information in the domains of healthcare, disease prevention, and health promotion [ 15 , 17 ]. It had good construct validity, item-scale convergent validity, internal consistency, and no floor or ceiling effect [ 17 ]. The survey also evaluated the determinants of vaccine acceptance such as contextual influences, individual and group influences, and vaccine-specific issues as recommended by the World Health Organization framework (online suppl.…”

Section: Methodsmentioning

confidence: 99%

“…In particular, there is a real threat of misinformation about COVID-19 vaccines following an unprecedented manner of accelerated vaccine development and testing in 2020 then near-global exhortation to vaccinate immediately after vaccines became available [ 15 ]. While early studies among healthcare workers and the general public noted vaccine hesitancy in up to 70% even among high-income countries [ 16 ], there is little information regarding COVID-19 vaccine acceptance in IgA nephropathy or immune-mediated disease [ 16 , 17 ]. The extensive media coverage of the available vaccines over the past year may have altered the health literacy and acceptance of COVID-19 vaccination, which appears to be here to stay for the medium- to long-term since health authorities are now advising booster vaccinations for immunocompromised hosts [ 18 ].…”

Section: Introductionmentioning

confidence: 99%

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A Descriptive Evaluation of Health Literacy and Determinants of COVID-19 Vaccine Acceptance among Patients with IgA Nephropathy with High Vaccine Uptake

Lim

Mok²,

Leeu³

et al. 2022

Glomerular Dis

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Aims: Shared decision-making regarding COVID-19 vaccination in IgA nephropathy involves the ability to handle health information regarding potential benefits and risk of flare, but few studies have evaluated health literacy in the context of vaccination. We aimed to evaluate the health literacy and COVID-19 vaccination uptake and acceptance in IgA nephropathy. Methods: Single-center cross-sectional study of 126 consecutive patients with IgA nephropathy. Health literacy was assessed using the HLS-EU-47 questionnaire. Determinants of vaccine acceptance such as contextual influences, individual and group influences, and vaccine-specific issues were adapted from the World Health Organization framework. Results: Forty-eight patients (38.1%) with IgAN nephropathy completed the survey between June and August 2021. The participants’ median age was 40.5 (31.6, 52.8) years with median disease duration of 2.8 (1.3, 4.3) years. The median general health literacy index was 31.74 (29.88, 35.82) with significantly greater difficulty in the competency of appraising health information and in the domain of disease prevention (p<0.001). Forty-five patients (93.8%) received at least one dose of COVID-19 vaccine between January and August 2021. Among the 3 unvaccinated patients, 2 intended to receive the vaccination while and 1 did not intend to get vaccinated. There was a high level of trust and belief that their government and healthcare providers had their best interests at heart and that the healthcare providers were honest about the vaccine’s risk and benefits, although 31.2% did not understand how the vaccine works and 22.9% believed that there were other ways to prevent infection. Most thought there was adequate safety information, were confident in the system for tracking adverse events and had no issues with access to the vaccine. Conclusion: Participants with IgA nephropathy had high health literacy scores and low vaccine hesitancy. The determinants for vaccine acceptance can guide efforts to optimize vaccination coverage.

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Section: Methodsmentioning

confidence: 99%