“…Epithelial cells incarceration in the stroma, resulting in cyst changes and accumulation of desquamated cell, has been supposed as possible cause (Bedford, 1997;Cullen and Grahn, 2001;Campos et al, 2002). The aetiology remains uncertain and corneal trauma or ulcer before the cyst formation has not could be concluded (Campos et al, 2002). However, most documented cases of CEIC in dogs reveals that surgical trauma or accidental corneal injuries could be the inciting factors (Koch et al, 1974;Schmidt and Prasse, 1976;Bedford et al, 1990).…”