Core-Shell Structured Theranostics

Guan, Qingwen; Wang, Min

doi:10.1142/s179398442141004x

Cited by 3 publications

(2 citation statements)

References 113 publications

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“…The silica-metal hybrids thus designed and fabricated can have both diagnostic and therapeutic capabilities. For the detailed discussions on this aspect, readers can refer to our recently published review article 48 . 50 , sodium alginate (SA) 51 and PLGA (poly-lactide-co-glycolide) 52 are widely used materials in tissue engineering and possess excellent properties, including non-toxicity, biocompatibility and biodegradability, as well as commercial availability.…”

Section: Ceramic-metal Hybridsmentioning

confidence: 99%

Hybrid ceramics-based cancer theranostics

Guan

Huang

et al. 2022

J. Korean Ceram. Soc.

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Cancer is a major threat to human lives. Early detection and precisely targeted therapy/therapies for cancer is the most effective way to reduce the difficulties (e.g., side effects, low survival rate, etc.) in treating cancer. To enable effective cancer detection and treatment, ceramic biomaterials have been intensively and extensively investigated owing to their good biocompatibility, high bioactivity, suitable biodegradability and other distinctive properties that are required for medical devices in oncology. Through hybridization with other materials and loading of imaging agents and therapeutic agents, nanobioceramics can form multifunctional nanodevices to simultaneously provide diagnostic and therapeutic functions for cancer patients, and these nanodevices are known as hybrid ceramics-based cancer theranostics. In this review, the recent developments of hybrid ceramics-based cancer theranostics, which include the key aspects such as their preparation, biological evaluation and applications, are summarized and discussed. The challenges and future perspectives for the clinical translation of hybrid ceramics-based cancer theranostics are also discussed. It is believed that the potential of hybrid ceramic nanoparticles as cancer theranostics is high and that the future of these theranostics is bright despite the difficulties along the way for their clinical translation.

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Section: Ceramic-metal Hybridsmentioning

confidence: 99%

Hybrid ceramics-based cancer theranostics

Guan

Huang

et al. 2022

J. Korean Ceram. Soc.

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“…По данным ВОЗ в мире наблюдается неуклонный рост онкологических больных. Только в США за 2021 г. зарегистрировано около 2 млн новых онкобольных [1].…”

Section: Introductionunclassified

IR spectral range small-sized laser-fiber fluorimeter for a luminescent photodiagnostics of tumors

Marechek,

Novichikhin,

Shilov

et al. 2023

JRE

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The results of the development of a small-sized laser fiber fluorimeter in the IR spectral range for a luminescent photodiagnostics of superficial localization tumors are presented. This device, working in conjunction with the “Fluroscan” type pharmaceutical composition based on the 2,4-di(α-methoxyethyl)deuteroporphyrin IX ytterbium complex dipotassium salt, ensures the achievement of high values of the luminescent diagnostic contrast index for a neoplasm/normal tissue. Import substitution of some basic design elements of the developed device, in particular the photodiode module, was carried out with a domestic analogue.

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