Coordination Chemistry of Some Terpyridyl-Polyamine Bridging Ligands

Abstract

A series of ditopic ligands bearing terpyridyl and polyamine coordination sites have been prepared. Complexes with RuII bound to the terpyridyl sites of many of these ligands have been prepared. RuII complexes of these ligands appear vulnerable to nucleophilic displacement of the polyamine portion of the ligand by BH4 –. A limited study of the coordination chemistry of the polyamine portion of the RuII complexes has been conducted, including the synthesis and characterization of RuII–CoIII heterodinuclear complexes in which the CoIII centre is coordinated by a cyclam macrocycle. The CoIII centre in these systems is unexpectedly labile – it can be removed from the polyamine upon treatment with ethane-1,2-diamine.

Synthesis and characterization of a new ditopic bipyridine-terpyridine bridging ligand using a Suzuki cross-coupling reaction

“…As part of our studies, we have been working on a research programme with the aim of synthesis of heterodinuclear complexes for the purpose of exploring the possibility of achieving light-induced ligand release. 1,2 In these studies, we are focussing on the preparation and use of ditopic bridging ligands where the two metal ion binding sites are differentiated either by the configuration of the binding sites or by the number of donor atoms in each site.…”

Synthesis of nitrogen mustards on cobalt(iii)

“…For some time we have been interested in the preparation of hetero-dinuclear metal complexes comprised of a Ru(II) component and a Co(III) component which are linked together through a ditopic ligand. [1][2][3][4][5][6][7][8] This interest stems from the desire to control the release of cytotoxic molecules through photoinduced electron transfer from the Ru(II) metal centre to the Co(III) metal centre via the ditopic bridging ligand (Scheme 1). 1,2,[9][10][11][12][13] The potential for release of cytotoxic ligands through reduction of Co(III) complexes has been explored, particularly in the context of exploiting the hypoxia seen in many solid tumours.…”

One-Pot Efficient Synthesis of 1,4-Bis (2,2′:6′,2′′-Terpyridin-4′-Yl) Benzene Ditopic Bridging Ligand

“…In the line of part of our studies, we conducted research projects involving preparation of poly-pyridine ditopic bridging ligands for the purpose of preparation of heterodinuclear Ru (II)-Co (III) complexes [1][2][3][4][5][6] In our studies, we have been interested in the preparation of bridging ligands in which at least one binding site was based on 2,2':6',2"-terpyridine ligand binding domain.…”