2012
DOI: 10.1001/2012.jama.11930
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Controlling Urban Epidemics of West Nile Virus Infection

Abstract: HIS SUMMER, DALLAS, TEXAS, HAS BEEN IN THE CENTER of its worst-ever regional epidemic of West Nile virus (WNV) infection, with one-quarter of the nation's cases identified in Dallas County. 1 With a record high number of trapped mosquitoes testing positive for WNV, from June 20 to August 21 WNV infections have been confirmed in 270 county residents; 160 have been hospitalized, 51 have required intensive care unit admission, and 11 have died. 2 Given this epidemic in Dallas, which has spilled over into Fort Wor… Show more

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Cited by 13 publications
(5 citation statements)
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“…This probability is further supported by the epidemic pattern in the United States, where ≈10 years after its introduction WNV is still causing large epidemics ( 10 ). Surveillance programs that can accurately determine public health risk and lead to timely vector control interventions are needed to prevent human infection.…”
mentioning
confidence: 86%
“…This probability is further supported by the epidemic pattern in the United States, where ≈10 years after its introduction WNV is still causing large epidemics ( 10 ). Surveillance programs that can accurately determine public health risk and lead to timely vector control interventions are needed to prevent human infection.…”
mentioning
confidence: 86%
“…The county of Dallas, Texas, experienced an epidemic of WNV infections in 2012. Surveillance reports revealed 25% of the cases in the United States were found in Dallas County ( 41 ). It shows for a vector-borne disease to have a successful transmission cycle several different factors need to be in place to affect the human population.…”
Section: Traditional Rural Infectious Diseases Turn Urbanmentioning
confidence: 99%
“…In this regard, a study carried out in Southern Italy concluded that vaccines used do not alter the overall hemogram picture and health status of horses though it is associated with modulation of humoral immunity, leukocyte populations, and inflammatory markers [ 24 ]. Contrariwise, to date, no vaccine is available for human [ 25 , 26 , 27 , 28 ]: Even though several vaccines targeting flaviviruses (e.g., TBE, yellow fever, Dengue, Japanese encephalitis, and Kyasanur forest disease) have been made available, none has been licensed for the use against WNV infection [ 29 , 30 , 31 ]. Moreover, none of the vaccine candidates has progressed further than to phase I/II clinical trial [ 32 ].…”
Section: Introductionmentioning
confidence: 99%