Controlled trial of zinc supplementation in anorexia nervosa

Narrative review of inpatient nutritional management of anorexia nervosa with management recommendations for Australian tertiary health services

“…The single study on the efficacy of 23,24 Alfred Health 25 The Royal Melbourne Hospital 29,30 Eastern Health [26][27][28] Western Health 31 RANZCP 10 zinc supplementation was performed 27 years ago and had a small sample size. 22 Although the study results revealed a significant increase in BMI with zinc supplementation, only three health service guidelines included multivitamin or trace element supplementation (which may contain zinc). This may be caused by uncertainty surrounding the optimal dosage of zinc, which may need evaluation in further studies.…”

“…We identified one double‐blind RCT comparing zinc supplementation with placebo 22 . Birmingham et al .…”

“…The need for and dosage of micronutrient supplementation is poorly studied. The single study on the efficacy of zinc supplementation was performed 27 years ago and had a small sample size 22 . Although the study results revealed a significant increase in BMI with zinc supplementation, only three health service guidelines included multivitamin or trace element supplementation (which may contain zinc).…”

Narrative review of inpatient nutritional management of anorexia nervosa with management recommendations for Australian tertiary health services

“…The single study on the efficacy of 23,24 Alfred Health 25 The Royal Melbourne Hospital 29,30 Eastern Health [26][27][28] Western Health 31 RANZCP 10 zinc supplementation was performed 27 years ago and had a small sample size. 22 Although the study results revealed a significant increase in BMI with zinc supplementation, only three health service guidelines included multivitamin or trace element supplementation (which may contain zinc). This may be caused by uncertainty surrounding the optimal dosage of zinc, which may need evaluation in further studies.…”

“…We identified one double‐blind RCT comparing zinc supplementation with placebo 22 . Birmingham et al .…”

“…The need for and dosage of micronutrient supplementation is poorly studied. The single study on the efficacy of zinc supplementation was performed 27 years ago and had a small sample size 22 . Although the study results revealed a significant increase in BMI with zinc supplementation, only three health service guidelines included multivitamin or trace element supplementation (which may contain zinc).…”

Micronutrient Status in Children Suffering From Anorexia Nervosa: A Cohort of 349 Patients in a Referral Center for Eating Disorders

“…Furthermore, a recent meta-analysis found that zinc supplementation improves height prognosis in young children with diarrhea (Mayo-Wilson et al 2014). In AN, zinc supplementation could promote weight gain, as demonstrated by a small interventional study of malnourished adult patients (Birmingham et al 1994). The authors suggest that normal levels of zinc improve the GABA neurotransmission system, which is impaired in AN and involved in the so-called "inhibitory" regulation of brain activity (Birmingham and Gritzner 2006).…”

Anorexia Nervosa in a 14-Year-Old Second-Generation Hispanic Adolescent Boy

“…As P.'s zinc levels were below normal range, he received zinc supplementation with his multivitamins. Zinc supplementation has been shown to help promote weight gain in AN patients, even those who are not suffering from a zinc deficiency (Birmingham et al 1994). It is not clear how zinc works in treatment of AN.…”

Narrative review of inpatient nutritional management of anorexia nervosa with management recommendations for Australian tertiary health services

“…The single study on the efficacy of 23,24 Alfred Health 25 The Royal Melbourne Hospital 29,30 Eastern Health [26][27][28] Western Health 31 RANZCP 10 zinc supplementation was performed 27 years ago and had a small sample size. 22 Although the study results revealed a significant increase in BMI with zinc supplementation, only three health service guidelines included multivitamin or trace element supplementation (which may contain zinc). This may be caused by uncertainty surrounding the optimal dosage of zinc, which may need evaluation in further studies.…”

“…We identified one double‐blind RCT comparing zinc supplementation with placebo 22 . Birmingham et al .…”

“…The need for and dosage of micronutrient supplementation is poorly studied. The single study on the efficacy of zinc supplementation was performed 27 years ago and had a small sample size 22 . Although the study results revealed a significant increase in BMI with zinc supplementation, only three health service guidelines included multivitamin or trace element supplementation (which may contain zinc).…”

Micronutrient Status in Children Suffering From Anorexia Nervosa: A Cohort of 349 Patients in a Referral Center for Eating Disorders

“…Furthermore, a recent meta-analysis found that zinc supplementation improves height prognosis in young children with diarrhea (Mayo-Wilson et al 2014). In AN, zinc supplementation could promote weight gain, as demonstrated by a small interventional study of malnourished adult patients (Birmingham et al 1994). The authors suggest that normal levels of zinc improve the GABA neurotransmission system, which is impaired in AN and involved in the so-called "inhibitory" regulation of brain activity (Birmingham and Gritzner 2006).…”

Anorexia Nervosa in a 14-Year-Old Second-Generation Hispanic Adolescent Boy

“…As P.'s zinc levels were below normal range, he received zinc supplementation with his multivitamins. Zinc supplementation has been shown to help promote weight gain in AN patients, even those who are not suffering from a zinc deficiency (Birmingham et al 1994). It is not clear how zinc works in treatment of AN.…”

Narrative review of inpatient nutritional management of anorexia nervosa with management recommendations for Australian tertiary health services

“…The single study on the efficacy of 23,24 Alfred Health 25 The Royal Melbourne Hospital 29,30 Eastern Health [26][27][28] Western Health 31 RANZCP 10 zinc supplementation was performed 27 years ago and had a small sample size. 22 Although the study results revealed a significant increase in BMI with zinc supplementation, only three health service guidelines included multivitamin or trace element supplementation (which may contain zinc). This may be caused by uncertainty surrounding the optimal dosage of zinc, which may need evaluation in further studies.…”

“…We identified one double‐blind RCT comparing zinc supplementation with placebo 22 . Birmingham et al .…”

“…The need for and dosage of micronutrient supplementation is poorly studied. The single study on the efficacy of zinc supplementation was performed 27 years ago and had a small sample size 22 . Although the study results revealed a significant increase in BMI with zinc supplementation, only three health service guidelines included multivitamin or trace element supplementation (which may contain zinc).…”

Micronutrient Status in Children Suffering From Anorexia Nervosa: A Cohort of 349 Patients in a Referral Center for Eating Disorders

“…Furthermore, a recent meta-analysis found that zinc supplementation improves height prognosis in young children with diarrhea (Mayo-Wilson et al 2014). In AN, zinc supplementation could promote weight gain, as demonstrated by a small interventional study of malnourished adult patients (Birmingham et al 1994). The authors suggest that normal levels of zinc improve the GABA neurotransmission system, which is impaired in AN and involved in the so-called "inhibitory" regulation of brain activity (Birmingham and Gritzner 2006).…”

Anorexia Nervosa in a 14-Year-Old Second-Generation Hispanic Adolescent Boy

“…As P.'s zinc levels were below normal range, he received zinc supplementation with his multivitamins. Zinc supplementation has been shown to help promote weight gain in AN patients, even those who are not suffering from a zinc deficiency (Birmingham et al 1994). It is not clear how zinc works in treatment of AN.…”