volume 19, issue 4, P261-266 1996
DOI: 10.1016/0141-0229(95)00244-8
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M.T. Moreira, A. Sanromán, G. Feijoo, J.M. Lema

Abstract: The application of a pulsing flow to fluidized-bed bioreactors in order to control pellet morphology of filamentous fungi was investigated. The operation at an optimum pulsation frequency allowed two effects: a narrower pellet size distribution which improves fluidization quality, and an enhanced production of citric acid by Aspergillus niger and manganese peroxidase by Phanerochaete chrysosporium. In the case of A. niger, the pellet diameter corresponding to the pulsed system operated at 0.35 s-1 was kept bet…

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