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citations
Cited by 150 publications
(118 citation statements)
references
References 56 publications
(118 reference statements)
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“…Alterations in endothelial cell behavior under different flow conditions has previously been demonstrated (Malek et al 1995). Endothelial cells are stimulated by shear, resulting in increased NOS expression (Tsao et al 1996;Ziegler et al 1998;Kader et al 2000) and SOD expression (Takeshita et al 2000).…”
Section: Shear Environmentmentioning
confidence: 89%
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“…Alterations in endothelial cell behavior under different flow conditions has previously been demonstrated (Malek et al 1995). Endothelial cells are stimulated by shear, resulting in increased NOS expression (Tsao et al 1996;Ziegler et al 1998;Kader et al 2000) and SOD expression (Takeshita et al 2000).…”
Section: Shear Environmentmentioning
confidence: 89%
“…Endothelial cell function and gene expression is also altered under different shear conditions, including laminar flow and oscillatory flow (Malek et al 1995;Ando et al 1996;Boyle et al 1997;Takahashi et al 1997;Traub et al 1998;Sorop et al 2003;Uhlenbrock et al 2003). Altered endothelial cell function is important in vascular disease states, as atherosclerotic lesions tend to form in regions with low shear stress or regions of oscillatory shear (De Keulenaer et al 1998;De Nigris et al 2001;).…”
Section: Gene Expressionmentioning
confidence: 99%
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“…The endothelium of the hyperkinetic cardiovascular system of people from stratum 3 are probably exposed to high sheer stress which could lead to damage of the endothelium and subsequent atherosclerosis and sustained hypertension in their later life. 42 …”
Section: Independent Variablementioning
confidence: 99%