Contribution of Frailty Markers in Explaining Differences Among Individuals in Five Samples of Older Persons

Sourial, Nadia; Bergman, Howard; Karunananthan, Sathya; Wolfson, Christina; Guralnik, Jack M.; Payette, Hélène; Robledo, Luis Miguel Gutiérrez; Deeg, Dorly J. H.; Fletcher, John; Puts, Maria T. E.; Zhu, Bin; Béland, François

doi:10.1093/gerona/gls084

Cited by 42 publications

(25 citation statements)

References 28 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…However, a very challenging point relates to the definition of phenotypic frailty, which includes physical activity as one of its moderately important domains (29). Is the association between midlife LTPA and old age frailty a "self-fulfilling prophecy" in our study?…”

Section: Discussionmentioning

confidence: 86%

Leisure-Time Physical Activity in Midlife Is Related to Old Age Frailty

Savela

Koistinen

Stenholm

et al. 2013

The Journals of Gerontology Series A: Biological Sciences and M

View full text Add to dashboard Cite

show abstract

Section: Discussionmentioning

confidence: 86%

Leisure-Time Physical Activity in Midlife Is Related to Old Age Frailty

Savela

Koistinen

Stenholm

et al. 2013

The Journals of Gerontology Series A: Biological Sciences and M

View full text Add to dashboard Cite

show abstract

“…It appears to be insensitive to changes in frailty severity and relatively nonspecific (especially in relation to comorbidities, such as cancer, parkinsonism, or musculoskeletal disorders, which might influence the presence or absence of the specific criteria). Additional items have been proposed to make up an expanded frailty phenotype, including affect and cognition [50,51]; on the other hand, some have proposed removing items so as to simplify the phenotype [52].…”

Section: Frailty As a Syndrome Or A Statementioning

confidence: 99%

Biologic aging, frailty, and age-related disease in chronic HIV infection

Brothers

Rockwood

2014

Current Opinion in HIV and AIDS

View full text Add to dashboard Cite

show abstract

“…Frailty domains appear to belong to a common construct, with physical strength being one of the discriminating characteristics. 6 Numerous other frailty definitions have been developed, for the most part based on one or the other of these 2 basic approaches.…”

mentioning

confidence: 99%

Frailty Consensus: A Call to Action

Morley¹,

Vellas²,

Kan³

et al. 2013

Journal of the American Medical Directors Association

3,120

2,393

View full text Add to dashboard Cite

Frailty is a clinical state in which there is an increase in an individual’s vulnerability for developing increased dependency and/or mortality when exposed to a stressor. Frailty can occur as the result of a range of diseases and medical conditions. A consensus group consisting of delegates from 6 major international, European, and US societies created 4 major consensus points on a specific form of frailty: physical frailty. Physical frailty is an important medical syndrome. The group defined physical frailty as “a medical syndrome with multiple causes and contributors that is characterized by diminished strength, endurance, and reduced physiologic function that increases an individual’s vulnerability for developing increased dependency and/or death.”Physical frailty can potentially be prevented or treated with specific modalities, such as exercise, protein-calorie supplementation, vitamin D, and reduction of polypharmacy.Simple, rapid screening tests have been developed and validated, such as the simple FRAIL scale, to allow physicians to objectively recognize frail persons.For the purposes of optimally managing individuals with physical frailty, all persons older than 70 years and all individuals with significant weight loss (≥5%) due to chronic disease should be screened for frailty.

show abstract

Contribution of Frailty Markers in Explaining Differences Among Individuals in Five Samples of Older Persons

Abstract: Our results provide further evidence supporting the notion that frailty domains may belong to a common construct. Physical strength may be the most important discriminating characteristic.

Cited by 42 publications

References 28 publications

Leisure-Time Physical Activity in Midlife Is Related to Old Age Frailty

Leisure-Time Physical Activity in Midlife Is Related to Old Age Frailty

Biologic aging, frailty, and age-related disease in chronic HIV infection

Frailty Consensus: A Call to Action

Contact Info

Product

Resources

About