2017
DOI: 10.1016/j.ijcard.2016.11.170
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Contrast media use in patients with chronic kidney disease undergoing coronary angiography: A systematic review and meta-analysis of randomized trials

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Cited by 34 publications
(23 citation statements)
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“…21,22 Numerous studies of patients undergoing coronary angiography have demonstrated AKI rates of w13%, which exceeds the average AKI rates of 5% to 6% associated with intravenous CM exposure. 13,[23][24][25] One conclusion of these results, although controversial, is that intra-arterial delivery of CM is more nephrotoxic compared to intravenous administration. [26][27][28] Statements that intra-arterial CM administration presents a higher concentration of CM to the kidney are only true when intra-arterial contrast is given in the aorta above or at the level of the renal arteries and possibly with high-dose left ventriculography (first-pass renal exposure).…”
Section: Comparison Of Cin With Intra-arterial and Intravenous Contramentioning
confidence: 99%
“…21,22 Numerous studies of patients undergoing coronary angiography have demonstrated AKI rates of w13%, which exceeds the average AKI rates of 5% to 6% associated with intravenous CM exposure. 13,[23][24][25] One conclusion of these results, although controversial, is that intra-arterial delivery of CM is more nephrotoxic compared to intravenous administration. [26][27][28] Statements that intra-arterial CM administration presents a higher concentration of CM to the kidney are only true when intra-arterial contrast is given in the aorta above or at the level of the renal arteries and possibly with high-dose left ventriculography (first-pass renal exposure).…”
Section: Comparison Of Cin With Intra-arterial and Intravenous Contramentioning
confidence: 99%
“…In literature there are various meta-analyses comparing LOCM and IOCM in terms of nephrotoxicity. Some studies conclude that there are no significant differences in the incidence of CI-AKI between LOCM and IOCM (Biondi-Zoccai et al, 2014;Eng et al, 2016;Heinrich et al, 2009;Pandya et al, 2017;Reed et al, 2009), but other studies report greater safety of the IOCM compared with LOCM (Laskey et al, 2009;Xiong et al, 2018). Most of the observational studies on "all-comers" patients did not find a higher profile of kidney safety for IOCM compared with LOCM (Azzalini et al, 2018b;Briguori et al, 2005).…”
Section: Contrast Media Osmolality To Reduce the Risk Of Contrast-indmentioning
confidence: 99%
“…However, clinical practice and most studies on CI nephropathy prefer the first definition as a simpler one with superior correlation with clinical outcomes [1,7,[16][17][18][19][20][21].…”
Section: Introductionmentioning
confidence: 99%