Continuous measurement of cardiac output by the Fick principle in infants and children: Comparison with the thermodilution method

“…(-0.45 to 0.52 l/min) for Fick-derived and FATD CO. Note how the scatter of results increases as CO increases obtained by Chang et al [13] (CI mean bias -0.01 ± 1.08 l/min per m 2 vs 0.02 ± 0.59 l/min per m 2 ) and Wippermann et al [14] (CO mean bias -0.05 ± 0.32 l/min vs 0.03 ± 0.48 l/min).…”

Section: Discussionmentioning

confidence: 84%

Clinical validation of cardiac output measurements using femoral artery thermodilution with direct Fick in ventilated children and infants

Tibby¹,

Hatherill²,

Marsh³

et al. 1997

Intensive Care Med

161

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“…During each study, right heart hemodynamic data including mean right atrial (RA) pressure, RV end-diastolic and endsystolic pressures, mean pulmonary artery pressure, and pulmonary capillary wedge (PCW) pressure were measured. Cardiac index was calculated using the Fick equation 17 and pulmonary vascular resistance (PVR; Wood Units) estimated by dividing the transpulmonary pressure gradient by cardiac index.…”

Section: Cardiac Catheterization Protocolmentioning

confidence: 99%

Cardiac Allograft Function During the First Year after Transplantation in Rejection-Free Children and Young Adults

Lunze

Colan

Gauvreau

et al. 2012

Circ: Cardiovascular Imaging

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Background-Allograft dysfunction is a common finding early after heart transplant (HT). We sought to assess the recovery of left (LV) and right ventricular (RV) function during the first year after HT in children and young adults using pulsedwave tissue Doppler imaging. Methods and Results-We analyzed serially performed echocardiography in 44 pediatric HT recipients (median age: 7.3 years at HT) who remained rejection-free during the first year post-transplant. Age-based normative values for systolic (S′), early-diastolic (E′), and late-diastolic (A′) velocities obtained using pulsed-wave tissue Doppler imaging in 380 healthy children were used to transform patient data into z scores. Pulsed-wave tissue Doppler imaging studies ≤10 days post-HT demonstrated biventricular systolic and diastolic dysfunction with most prominent impairment in RV systolic function (S′ z score −2.7±0.8), RV early-diastolic filling (E′ z score −2.3±1.1), and LV early-diastolic filling (E′ z score −2.3±1.1). LV systolic function (S′ z score) and late-diastolic filling (A′ z score) improved to normal in 11 to 30 days, LV early-diastolic filling (E′ z score) in 4 to 6 months, and RV early-diastolic filling in 6 to 9 months (P<0.001 for all on longitudinal analysis). However, RV systolic function (RV S′ z score −1.2±1.1) remained impaired 1-year post-transplant. Analysis of serial cardiac catheterization studies showed that RV and LV filling pressures were elevated early post-HT and declined gradually during the first year post-transplant. Conclusions-Pediatric

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“…This measurement technique has been shown to be accurate and useful in the management of critically ill patients (Baele et al 1982;Burchell et al 1997;Fahey et al 1984), pediatric patients (Wippermann et al 1996) and patients undergoing cardiac surgery (Waller et al 1982). Continuous measurements of SvO 2 are also potentially useful in patients with left ventricular dysfunction for studying physiological mechanisms determining the response to exercise (Sullivan et al 1989), recovery from exercise (Sumimoto et al 1993) and for the assessment of continuous cardiac output during exercise using the continuous Fick method (Matsumoto et al 1999;Nakanishi et al 1993).…”

Section: Introductionmentioning

confidence: 99%

The reliability of continuous measurement of mixed venous oxygen saturation during exercise in patients with chronic heart failure

Sleutjes

Kemps²,

Thijssen³

et al. 2007

Eur J Appl Physiol

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Continuous assessment of mixed venous oxygen saturation (cSvO(2)) during exercise using a fiber optic pulmonary artery catheter can provide valuable information on the physiological determinants of the exercise capacity in patients with chronic heart failure (CHF). Since its accuracy is not well established during exercise, this study evaluated the reliability of a fiber optic pulmonary artery catheter for measuring SvO(2 )during exercise in CHF patients. Ten patients with stable CHF performed steady-state exercise tests at 30 and 80% of the ventilatory threshold and consequently a symptom-limited incremental exercise test. During the tests, SvO(2 )was monitored continuously using a fiber optic pulmonary artery catheter (CCOmbo, Edwards Lifesciences, Irvine, CA, USA) and by oximetric analysis of mixed venous blood samples obtained at rest (n = 26), steady state (n = 17) and peak exercise (n = 8). There was a significant correlation between oximetrically determined SvO(2) and cSvO(2) values (r = 0.97). The bias between both methods was 0.6% with limits of agreement from -8 to 9%. The limits of agreement for SvO(2 )values <30% (n = 16) were slightly wider than for SvO(2) values >30% (n = 35) (from -10 to 12% and from -7 to 8%, respectively). In conclusion, continuous measurement of SvO(2 )during exercise using a fiber optic pulmonary catheter is reliable in patients with CHF, with somewhat less accurate measurements of SvO(2 )below 30%.

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Continuous measurement of cardiac output by the Fick principle in infants and children: Comparison with the thermodilution method

Abstract: Continuous measurement of cardiac output by the Fick principle offers a convenient method for the hemodynamic monitoring of unstable infants and children.

Cited by 39 publications

References 21 publications

Clinical validation of cardiac output measurements using femoral artery thermodilution with direct Fick in ventilated children and infants

Clinical validation of cardiac output measurements using femoral artery thermodilution with direct Fick in ventilated children and infants

Cardiac Allograft Function During the First Year after Transplantation in Rejection-Free Children and Young Adults

The reliability of continuous measurement of mixed venous oxygen saturation during exercise in patients with chronic heart failure

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