Continuous and Noninvasive Blood Pressure Measurement: A Novel Modeling Methodology of the Relationship Between Blood Pressure and Pulse Wave Velocity

Chen, Yan; Chen, Wen; Tao, Guocai; Bi, Min; Li, Guoqi

doi:10.1007/s10439-009-9759-1

Cited by 105 publications

(71 citation statements)

References 11 publications

(29 reference statements)

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“…Similar nonlinear relations between BP and brachial-ankle PWV were described by Yamashina et al 2003 in human beings. Other authors obtained a non-linear relationship between PVW and BP, which was inverted to that of the above cited studies (Chen et al 2009;Zheng and Murray 2009). Linear as well as non-linear PTT-BP functions have been described in isolated canine common carotid arteries (Callaghan et al 1984), while a number of authors reported linear relations (Geddes et al 1981;Payne et al 2006).…”

Section: Discussionmentioning

confidence: 80%

Continuous blood pressure measurement by using the pulse transit time: comparison to a cuff-based method

Gesche

D²,

Küchler³

et al. 2011

Eur J Appl Physiol

406

263

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Pulse transit time (PTT) and pulse wave velocity (PWV), respectively, were shown to have a correlation with systolic blood pressure (SBP) and have been reported to be suitable for indirect BP measurements. The aim of this study was to create a function between SBP and PWV, and to test its reliability for the determination of absolute SBP using a non-linear algorithm and a one-point calibration. 63 volunteers performed exercise to induce rises in BP. Arterial PTT was measured between the R-spike of the ECG and the plethysmographic curve of finger pulse-oximetry. The reference BP was measured using a cuff-based sphygmomanometric aneroid device. Data from 13 of the 63 volunteers served for the detection of the PWV-BP relationship. The created non-linear function was used to calculate BP values after individual correction for the BP offset in a group of 50 volunteers. Individual correlation coefficients for SBP measured by PTT (SBP(PTT)) and by cuff (SBP(CUFF)) varied between r = 0.69 and r = 0.99. Taking all data together, we found r = 0.83 (276 measurements in 50 volunteers). In the Bland-Altman plot, the limits of agreement were [Formula: see text]± 19.8 mmHg. In conclusion, comparing SBP values using the PTT-based method and those measured by cuff resulted in a significant correlation. However, the Bland-Altman plot shows relevant differences between both methods, which are partly due to greater variability of the SBP(PTT) measurement during intensified exercise. Results suggest that PTT can be used for measuring absolute SBP when performing an individual correction for the offset of the BP-PWV relation.

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Section: Discussionmentioning

confidence: 80%

Continuous blood pressure measurement by using the pulse transit time: comparison to a cuff-based method

Gesche

D²,

Küchler³

et al. 2011

Eur J Appl Physiol

406

263

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show abstract

“…Ears, toes and fingers are common sites used for measurement [60]. PTT f measured from the foot of one PPG to that of another has been demonstrated to have a strong correlation to invasive DBP [61], but a study on 44 normotensive male subjects concluded otherwise [62]. The peaks of PPG that theoretically represent SBP have been found to be unreliable indicators of SBP.…”

Section: Pulse Transit Time (Ptt)mentioning

confidence: 99%

“…The logarithmic model Equation (6) approaches negative infinity as "Time Delay" tends to zero, making it difficult to use this relationship to represent small BP [61].…”

Section: Logarithmic Modelmentioning

confidence: 99%

Cuff-Less and Continuous Blood Pressure Monitoring: A Methodological Review

et al. 2017

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Blood pressure (BP) is one of the most important monitoring parameters in clinical medicine. For years, the cuff-based sphygmomanometer and the arterial invasive line have been the gold standards for care professionals to assess BP. During the past few decades, the wide spread of the oscillometry-based BP arm or wrist cuffs have made home-based BP assessment more convenient and accessible. However, the discontinuous nature, the inability to interface with mobile applications, the relative inaccuracy with movement, and the need for calibration have rendered those BP oscillometry devices inadequate for next-generation healthcare infrastructure where integration and continuous data acquisition and communication are required. Recently, the indirect approach to obtain BP values has been intensively investigated, where BP is mathematically derived through the "Time Delay" in propagation of pressure waves in the vascular system. This holds promise for the realization of cuffless and continuous BP monitoring systems, for both patients and healthy populations in both inpatient and outpatient settings. This review highlights recent efforts in developing these next-generation blood pressure monitoring devices and compares various mathematical models. The unmet challenges and further developments that are crucial to develop "Time Delay"-based BP devices are also discussed.

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“…We previously proposed a BP-PWV model and validated it with DBP measurements from a small population of subjects with no evidence of cardiovascular disease. 8 PWV d was determined by the commonly used foot-tofoot method. However, we previously felt difficult to determine proper PWV s because the shape of the pulse wavecrest changed unpredictably due to various influencing factors.…”

Section: Introductionmentioning

confidence: 99%

Continuous and Noninvasive Measurement of Systolic and Diastolic Blood Pressure by One Mathematical Model with the Same Model Parameters and Two Separate Pulse Wave Velocities

Chen

Tao

et al. 2011

Ann Biomed Eng

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There is keen interest in continuous and noninvasive blood pressure (BP) measurement. However, many technologies have a shortcoming of complex mechanical structure. In our study, two arterial pulses are acquired by photoplethysmography (PPG) at ear and toe in order to explore a new method of measuring BP by pulse wave velocity (PWV). We previously validated and reported a BP-PWV mathematical model with measurements from humans with no evidence of cardiovascular disease, but were only able to determine PWV related to diastolic blood pressure (DBP). In this paper, we propose methods of identifying pulse transmit time (PTT) in low, normal and high systolic blood pressure (SBP) conditions. By averaging the PTT's of incident wave and reflected wave for non-systematic error reduction, we obtain a PWV that is suitable for estimating SBP. SBP and DBP are estimated by two separate PWV's based on the previously calibrated models. Experimental measurements are conducted on 26 subjects (age 19 ± 1 and 60 ± 1) with no evidence of cardiovascular disease. The measurement errors (Mean Deviation = 2.16 mmHg (SBP) and 1.49 mmHg (DBP); Standard Deviation = 6.23 mmHg (SBP) and 6.51 mmHg (DBP)) satisfy the accuracy criteria of Association for the Advancement of Medical Instrumentation. The results verify that SBP and DBP can be estimated by one mathematical model with the same model parameters and two separate PWV's.

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Continuous and Noninvasive Blood Pressure Measurement: A Novel Modeling Methodology of the Relationship Between Blood Pressure and Pulse Wave Velocity

Cited by 105 publications

References 11 publications

Continuous blood pressure measurement by using the pulse transit time: comparison to a cuff-based method

Continuous blood pressure measurement by using the pulse transit time: comparison to a cuff-based method

Cuff-Less and Continuous Blood Pressure Monitoring: A Methodological Review

Continuous and Noninvasive Measurement of Systolic and Diastolic Blood Pressure by One Mathematical Model with the Same Model Parameters and Two Separate Pulse Wave Velocities

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